This review covers recent developments in the area of particle engineering via spray drying.
The last decade has seen a shift from empirical formulation efforts to an engineering …

Remarkably, with the exception of anaesthetic gases, the ancient human practice of inhaling
substances into the lungs for systemic effect has only just begun to be adopted by modern …

A new type of inhalation aerosol, characterized by particles of small mass density and large
size, permitted the highly efficient delivery of inhaled therapeutics into the systemic …

Drug delivery systems are widely researched and developed to improve the delivery of
pharmaceutical compounds and molecules. The last few decades have seen a marked …

The lung is naturally permeable to all small-molecule drugs studied and to many therapeutic
peptides and proteins. Absorption can be estimated using a simple animal test, intratracheal …

Dry powder inhaler (DPI) products have traditionally comprised a simple formulation of
micronised drug mixed with a carrier excipient, typically lactose monohydrate. The presence …

It is well established that strict glycemic control (hemoglobin A 1c< 7.0%) can prevent the
microvascular complications of diabetes mellitus. Recent studies indicate that elevated …

Attempts at replicating physiological insulin secretion, as a means of restoring the normal
metabolic milieu and thereby minimizing the risk of diabetic complications, has become an …

A wide range of dry powder inhaler (DPI) devices are currently available on the market to
deliver drugs into lungs with a view to maximise drug delivery with low variability. DPIs also …

We examine the role of defaults in high-frequency, small-scale choices using unique data on
over 13 million New York City taxi rides. Using a regression discontinuity design, we show …