One hundred and fifty years ago, Johann Thudichum described sphingolipids as unusual
“Sphinx-like” lipids from the brain. Today, we know that thousands of sphingolipid molecules …

Sphingolipids are a class of complex lipids containing a backbone of sphingoid bases,
namely the organic aliphatic amino alcohol sphingosine (Sph), that are essential …

Sphingolipids (SLs) are fundamental components of eukaryotic cells. 1-Deoxysphingolipids
differ structurally from canonical SLs as they lack the essential C1-OH group. Consequently …

Lysosomes are acidic organelles essential for degradation, signalling and cell
homoeostasis. In addition, they play a key role in cell death. Permeabilization of the …

The synthesis, characterization, optical, and fluorescent properties of an amphiphilic Schiff-
base bis (salicylaldiminato) zinc (II) complex are reported. Detailed 1H nuclear magnetic …

Sphingoid bases encompass a group of long chain amino alcohols which form the essential
structure of sphingolipids. Over the last years, these amphiphilic molecules were moving …

The synthesis, characterization, 1H NMR, optical absorption and fluorescent properties of a
series of amphiphilic Schiff-base bis (salicylaldiminato) zinc (II) complexes are reported …

Biallelic mutations in the glucocerebrosidase (GBA1) gene cause Gaucher disease,
characterized by lysosomal accumulation of glucosylceramide and glucosylsphingosine in …

Some of the simplest sphingolipids, namely sphingosine, ceramide and their
phosphorylated compounds [sphingosine 1-phosphate (Sph-1-P) and ceramide 1 …

The study of gases, clusters, liquids, and solids as units or systems, eventually focuses on
the properties of these systems as governed by interactions between atoms, molecules, and …