Behavior is tightly synchronized with bodily physiology. Internal needs from the body drive
behavior selection, while optimal behavior performance requires a coordinated …

The dorsal vagal complex contains three structures: the area postrema, the nucleus tractus
solitarii, and the dorsal motor nucleus of the vagus. These structures are tightly linked, both …

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Background IL-2 regulates T cell differentiation: low-dose IL-2 induces immunoregulatory
Treg differentiation, while high-dose IL-2 acts as a potent activator of cytotoxic T cells and …

The use of preventive tuberculosis treatment after Mycobacterium tuberculosis infection,
historically with isoniazid and more recently with shorter-duration rifamycin regimens, is a …

Background Cancer cachexia significantly contributes to morbidity and mortality in patients
with non‐small‐cell lung cancer (NSCLC). Inflammatory pathways mediated by interleukin‐6 …

Metabolic reprogramming of cancer cells and the tumour microenvironment are pivotal
characteristics of cancers, and studying these processes offer insights and avenues for …

In pancreatic cancer, significant alterations occur in the local nervous system, including
axonogenesis, neural remodeling, perineural invasion, and perineural neuritis. Pancreatic …

Our approaches toward understanding cancer have evolved beyond cell-intrinsic and local
microenvironmental changes within the tumor to encompass how the cancer interfaces with …

Recent work has highlighted the central role the brain–body axis plays in not only
maintaining organismal homeostasis but also coordinating the body's response to immune …