Vitamin E is a lipid soluble vitamin comprising of eight natural isoforms, namely, α, β, δ, γ
isoforms of tocopherol and α, β, δ, γ isoforms of tocotrienol. Many studies have been …

The therapeutic potential of the tocotrienol group stems from its nutraceutical properties as a
dietary supplement. It is largely considered to be safe when consumed at low doses for …

Despite the significant advancements in the diagnosis and treatment of cancer, it still
remains one of the most fatal diseases in the world due to the lack of sensitive diagnosis …

Chemoresistance is the adaptation of cancer cells against therapeutic agents. When
exhibited by cancer cells, chemoresistance helps them to avoid apoptosis, cause relapse …

γ-Tocotrienol, a member of the vitamin E family of compounds, displays potent
antiproliferative and cytotoxic effects in a variety of cancer cell types at treatment doses that …

Tocotrienol (T3), unsaturated vitamin E, is gaining a lot of attention owing to its potent
anticancer effect, since its efficacy is much greater than that of tocopherol (Toc). Various …

Tocotrienols (T3s) are a subclass of unsaturated vitamin E that have been extensively
studied for their anti-proliferative, anti-oxidative and anti-inflammatory properties in …

A large percentage of human breast cancers are characterized by excessive or aberrant
HER2 activity. Lipid rafts are specialized microdomains within the plasma membrane that …

Tumor metastasis involves some of the most complex and dynamic processes in cancer,
often leading to poor quality of life and inevitable death. The search for therapeutic …

Mitochondrial dysfunction plays a major role in the development of age-related
neurodegenerative diseases and recent evidence suggests that food ingredients can …