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Breathing matters
Breathing is a well-described, vital and surprisingly complex behaviour, with behavioural
and physiological outputs that are easy to directly measure. Key neural elements for …
and physiological outputs that are easy to directly measure. Key neural elements for …
Brainstem respiratory networks: building blocks and microcircuits
Breathing movements in mammals are driven by rhythmic neural activity generated within
spatially and functionally organized brainstem neural circuits comprising the respiratory …
spatially and functionally organized brainstem neural circuits comprising the respiratory …
Understanding the rhythm of breathing: so near, yet so far
Breathing is an essential behavior that presents a unique opportunity to understand how the
nervous system functions normally, how it balances inherent robustness with a highly …
nervous system functions normally, how it balances inherent robustness with a highly …
Skn-1a/Pou2f3 functions as a master regulator to generate Trpm5-expressing chemosensory cells in mice
J Yamashita, M Ohmoto, T Yamaguchi, I Matsumoto… - PloS one, 2017 - journals.plos.org
Transient receptor potential channel M5 (Trpm5)-expressing cells, such as sweet, umami,
and bitter taste cells in the oropharyngeal epithelium, solitary chemosensory cells in the …
and bitter taste cells in the oropharyngeal epithelium, solitary chemosensory cells in the …
Flufenamic acid as an ion channel modulator
R Guinamard, C Simard, C Del Negro - Pharmacology & therapeutics, 2013 - Elsevier
Flufenamic acid has been known since the 1960s to have anti-inflammatory properties
attributable to the reduction of prostaglandin synthesis. Thirty years later, flufenamic acid …
attributable to the reduction of prostaglandin synthesis. Thirty years later, flufenamic acid …
9‐phenanthrol inhibits human TRPM4 but not TRPM5 cationic channels
T Grand, M Demion, C Norez, Y Mettey… - British journal of …, 2008 - Wiley Online Library
Background and purpose: TRPM4 and TRPM5 are calcium‐activated non‐selective cation
channels with almost identical characteristics. TRPM4 is detected in several tissues …
channels with almost identical characteristics. TRPM4 is detected in several tissues …
Defining the rhythmogenic elements of mammalian breathing
Breathing's remarkable ability to adapt to changes in metabolic, environmental, and
behavioral demands stems from a complex integration of its rhythm-generating network …
behavioral demands stems from a complex integration of its rhythm-generating network …
TRPs in the brain
The Transient receptor potential (TRP) family of cation channels is a large protein family,
which is mainly structurally uniform. Proteins consist typically of six transmembrane domains …
which is mainly structurally uniform. Proteins consist typically of six transmembrane domains …
Transient receptor potential channels meet phosphoinositides
Transient receptor potential (TRP) cation channels are unique cellular sensors that are
involved in multiple cellular functions, ranging from transduction of sensory signals to the …
involved in multiple cellular functions, ranging from transduction of sensory signals to the …
State-dependent interactions between excitatory neuromodulators in the neuronal control of breathing
All neuronal networks are modulated by multiple neuropeptides and biogenic amines. Yet,
few studies investigate how different modulators interact to regulate network activity. Here …
few studies investigate how different modulators interact to regulate network activity. Here …