Leptin and obesity: role and clinical implication

M Obradovic, E Sudar-Milovanovic, S Soskic… - Frontiers in …, 2021 - frontiersin.org
The peptide hormone leptin regulates food intake, body mass, and reproductive function and
plays a role in fetal growth, proinflammatory immune responses, angiogenesis and lipolysis …

Iron deficiency anaemia

A Lopez, P Cacoub, IC Macdougall, L Peyrin-Biroulet - The Lancet, 2016 - thelancet.com
Anaemia affects roughly a third of the world's population; half the cases are due to iron
deficiency. It is a major and global public health problem that affects maternal and child …

Receiver-operating characteristic (ROC) plots: a fundamental evaluation tool in clinical medicine

MH Zweig, G Campbell - Clinical chemistry, 1993 - academic.oup.com
The clinical performance of a laboratory test can be described in terms of diagnostic
accuracy, or the ability to correctly classify subjects into clinically relevant subgroups …

[BOOK][B] WHO guideline on use of ferritin concentrations to assess iron status in populations

World Health Organization - 2020 - books.google.com
This guideline provides global, evidence-informed recommendations on the use of
indicators for assessing a population's iron status and application of the use of ferritin …

Users' guides to the medical literature: III. How to use an article about a diagnostic test B. What are the results and will they help me in caring for my patients?

R Jaeschke, GH Guyatt, DL Sackett, G Guyatt, E Bass… - Jama, 1994 - jamanetwork.com
CLINICAL SCENARIO You are back where we put you in the previous article 1 on diagnostic
tests in this series on how to use the medical literature: in the library studying an article that …

British Society of Gastroenterology guidelines for the management of iron deficiency anaemia in adults

J Snook, N Bhala, ILP Beales, D Cannings, C Kightley… - Gut, 2021 - gut.bmj.com
Iron deficiency anaemia (IDA) is a major cause of morbidity and burden of disease
worldwide. It can generally be diagnosed by blood testing and remedied by iron …

[HTML][HTML] Reverse epidemiology of cardiovascular risk factors in maintenance dialysis patients

K Kalantar-Zadeh, G Block, MH Humphreys… - Kidney international, 2003 - Elsevier
Reverse epidemiology of cardiovascular risk factors in maintenance dialysis patients.
Conventional risk factors of cardiovascular disease and mortality in the general population …

Serum ferritin: past, present and future

W Wang, MA Knovich, LG Coffman, FM Torti… - Biochimica et Biophysica …, 2010 - Elsevier
BACKGROUND: Serum ferritin was discovered in the 1930s, and was developed as a
clinical test in the 1970s. Many diseases are associated with iron overload or iron deficiency …

Guidelines for the management of iron deficiency anaemia

AF Goddard, MW James, AS McIntyre, BB Scott - Gut, 2011 - gut.bmj.com
Background Iron deficiency anaemia (IDA) occurs in 2–5% of adult men and
postmenopausal women in the developed world and is a common cause of referral to …

Criteria for iron deficiency in patients with heart failure

G Masini, FJ Graham, P Pellicori, JGF Cleland… - Journal of the American …, 2022 - jacc.org
Background Guidelines on heart failure (HF) define iron deficiency (ID) as a serum ferritin<
100 ng/mL or, when 100-299 ng/mL, a transferrin saturation (TSAT)< 20%. Inflammation …