Oral antioxidant and lutein/zeaxanthin supplements slow geographic atrophy progression to the fovea in age-related macular degeneration
Purpose To determine whether oral micronutrient supplementation slows geographic
atrophy (GA) progression in age-related macular degeneration (AMD). Design Post hoc …
atrophy (GA) progression in age-related macular degeneration (AMD). Design Post hoc …
Geographic atrophy: Pathophysiology and current therapeutic strategies
Geographic atrophy (GA) is an advanced stage of age-related macular degeneration (AMD)
that leads to gradual and permanent vision loss. GA is characterized by the loss of …
that leads to gradual and permanent vision loss. GA is characterized by the loss of …
Reticular pseudodrusen status, ARMS2/HTRA1 genotype, and geographic atrophy enlargement: Age-Related Eye Disease Study 2 Report 32
Purpose To determine whether reticular pseudodrusen (RPD) status, ARMS2/HTRA1
genotype, or both are associated with altered geographic atrophy (GA) enlargement rate …
genotype, or both are associated with altered geographic atrophy (GA) enlargement rate …
[HTML][HTML] Age-related macular degeneration: what do we know so far?
HH Ma, R Liutkevičienė - Acta medica Lituanica, 2021 - ncbi.nlm.nih.gov
Ageing is a natural process that everyone experiences and nobody is an exception. With
ageing, our body experiences physiological changes. In this article, the focus is made on the …
ageing, our body experiences physiological changes. In this article, the focus is made on the …
Association of complement C3 inhibitor pegcetacoplan with reduced photoreceptor degeneration beyond areas of geographic atrophy
Preservation of photoreceptors beyond areas of retinal pigment epithelium atrophy is a
critical treatment goal in eyes with geographic atrophy (GA) to prevent vision loss. Thus, we …
critical treatment goal in eyes with geographic atrophy (GA) to prevent vision loss. Thus, we …
[HTML][HTML] Systems genomics in age-related macular degeneration
AI den Hollander, RF Mullins, LD Orozco… - Experimental eye …, 2022 - Elsevier
Genomic studies in age-related macular degeneration (AMD) have identified genetic
variants that account for the majority of AMD risk. An important next step is to understand the …
variants that account for the majority of AMD risk. An important next step is to understand the …
[HTML][HTML] Geographic atrophy in age-related macular degeneration: a tale of two stages
TDL Keenan - Ophthalmology Science, 2023 - Elsevier
Purpose To examine disease progression in age-related macular degeneration (AMD) at 2
distinct stages, progression to geographic atrophy (GA) versus GA expansion, by …
distinct stages, progression to geographic atrophy (GA) versus GA expansion, by …
Enlargement of geographic atrophy from first diagnosis to end of life
JM Colijn, B Liefers, N Joachim, T Verzijden… - JAMA …, 2021 - jamanetwork.com
Importance Treatments for geographic atrophy (GA), a late stage of age-related macular
degeneration (AMD), are currently under development. Understanding the natural course is …
degeneration (AMD), are currently under development. Understanding the natural course is …
[HTML][HTML] A deep learning model for segmentation of geographic atrophy to study its long-term natural history
B Liefers, JM Colijn, C González-Gonzalo, T Verzijden… - Ophthalmology, 2020 - Elsevier
Purpose To develop and validate a deep learning model for the automatic segmentation of
geographic atrophy (GA) using color fundus images (CFIs) and its application to study the …
geographic atrophy (GA) using color fundus images (CFIs) and its application to study the …
An update on the hemodynamic model of age-related macular degeneration
PURPOSE To provide an update on the hemodynamic model of age-related macular
degeneration (AMD). DESIGN Evidence-based perspective. METHODS Review of the …
degeneration (AMD). DESIGN Evidence-based perspective. METHODS Review of the …