The high rates of morbidity and mortality caused by fungal infections are associated with the
current limited antifungal arsenal and the high toxicity of the compounds. Additionally …

Dermatophytoses or tinea refers to superficial fungal infection of keratinized tissues.
Although generally considered easy to treat, recalcitrant infections, presenting as extensive …

Background An alarming increase in recalcitrant dermatophytosis has been witnessed in
India over the past decade. Drug resistance may play a major role in this scenario …

Dermatophytes are common causes of skin, hair, and nail infections in humans. The most
common species causing infections in humans are Trichophyton rubrum, Trichophyton …

Terbinafine is one of the allylamine antifungal agents whose target is squalene epoxidase
(SQLE). This agent has been extensively used in the therapy of dermatophyte infections …

Numerous reports describe the emergence of resistance in dermatophytes, especially in T.
rubrum and T. mentagrophytes/indotineae strains. We here present a review of the current …

During the past decade, a prolonged and serious outbreak of dermatophytosis due to a
terbinafine-resistant novel species in the Trichophyton mentagrophytes-T. interdigitale …

The increasing incidence and changing epidemiology of invasive fungal infections continue
to present many challenges to their effective management. The repertoire of antifungal drugs …

The burden of fungal infections is not widely appreciated. Although these infections are
responsible for over one million deaths annually, it is estimated that one billion people are …

Dermatophytes comprise pathogenic fungi that have a high affinity for the keratinized
structures present in nails, skin, and hair, causing superficial infections known as …