The multiple signaling systems regulating virulence in Pseudomonas aeruginosa

P Nadal Jimenez, G Koch, JA Thompson… - Microbiology and …, 2012 - Am Soc Microbiol
Cell-to-cell communication is a major process that allows bacteria to sense and coordinately
react to the fluctuating conditions of the surrounding environment. In several pathogens, this …

Look who's talking: communication and quorum sensing in the bacterial world

P Williams, K Winzer, WC Chan… - … Transactions of the …, 2007 - royalsocietypublishing.org
For many years bacteria were considered primarily as autonomous unicellular organisms
with little capacity for collective behaviour. However, we now appreciate that bacterial cells …

6-Gingerol reduces Pseudomonas aeruginosa biofilm formation and virulence via quorum sensing inhibition

HS Kim, SH Lee, Y Byun, HD Park - Scientific reports, 2015 - nature.com
Pseudomonas aeruginosa is a well-known pathogenic bacterium that forms biofilms and
produces virulence factors via quorum sensing (QS). Interfering with normal QS interactions …

Social cheating in Pseudomonas aeruginosa quorum sensing

KM Sandoz, SM Mitzimberg… - Proceedings of the …, 2007 - National Acad Sciences
In a process termed quorum sensing, bacteria use diffusible chemical signals to coordinate
cell density-dependent gene expression. In the human pathogen Pseudomonas aeruginosa …

Detection of quorum-sensing N-acyl homoserine lactone signal molecules by bacterial biosensors

L Steindler, V Venturi - FEMS microbiology letters, 2007 - academic.oup.com
Many Gram-negative bacteria use N-acyl homoserine lactones (AHLs) as quorum-sensing
(QS) signal molecules. AHL QS has been the subject of extensive investigation in the last …

The third quorum-sensing system of Pseudomonas aeruginosa: Pseudomonas quinolone signal and the enigmatic PqsE protein

S García-Reyes, G Soberón-Chávez… - Journal of medical …, 2020 - microbiologyresearch.org
Pseudomonas aeruginosa is an opportunistic pathogen that produces several virulence
factors such as lectin A, pyocyanin, elastase and rhamnolipids. These compounds are …

Global regulatory pathways and cross-talk control Pseudomonas aeruginosa environmental lifestyle and virulence phenotype

KA Coggan, MC Wolfgang - Current issues in molecular biology, 2012 - mdpi.com
Pseudomonas aeruginosa is a metabolically versatile environmental bacterium and an
opportunistic human pathogen that relies on numerous signaling pathways to sense …

Biomolecular Mechanisms of Pseudomonas aeruginosa and Escherichia coli Biofilm Formation

G Laverty, SP Gorman, BF Gilmore - Pathogens, 2014 - mdpi.com
Pseudomonas aeruginosa and Escherichia coli are the most prevalent Gram-negative
biofilm forming medical device associated pathogens, particularly with respect to catheter …

Core principles of bacterial autoinducer systems

BA Hense, M Schuster - Microbiology and Molecular Biology …, 2015 - Am Soc Microbiol
Autoinduction (AI), the response to self-produced chemical signals, is widespread in the
bacterial world. This process controls vastly different target functions, such as luminescence …

An update on the sociomicrobiology of quorum sensing in gram-negative biofilm development

D Passos da Silva, MC Schofield, MR Parsek… - Pathogens, 2017 - mdpi.com
Bacteria are social creatures that are able to interact and coordinate behaviors with each
other in a multitude of ways. The study of such group behaviors in microbes was coined …