Measuring DNA modifications with the comet assay: a compendium of protocols

A Collins, P Møller, G Gajski, S Vodenková… - Nature protocols, 2023 - nature.com
The comet assay is a versatile method to detect nuclear DNA damage in individual
eukaryotic cells, from yeast to human. The types of damage detected encompass DNA …

Blue mussels (Mytilus edulis spp.) as sentinel organisms in coastal pollution monitoring: a review

J Beyer, NW Green, S Brooks, IJ Allan, A Ruus… - Marine environmental …, 2017 - Elsevier
The blue mussel (Mytilus spp.) is widely used as a bioindicator for monitoring of coastal
water pollution (mussel watch programs). Herein we provide a review of this study field with …

Comet assay: a versatile but complex tool in genotoxicity testing

E Cordelli, M Bignami, F Pacchierotti - Toxicology Research, 2021 - academic.oup.com
The comet assay is a versatile method for measuring DNA strand breaks in individual cells. It
can also be applied to cells isolated from treated animals. In this review, we highlight …

Chronic and Transgenerational Effects of Polystyrene Microplastics at Environmentally Relevant Concentrations in Earthworms (Eisenia fetida)

Z Sobhani, L Panneerselvan, C Fang… - Environmental …, 2021 - academic.oup.com
Recently, soil contamination with microplastics has emerged as a serious global
environmental concern that has necessitated more research on their potential impacts on …

Ecotoxicological effects of petroleum-contaminated soil on the earthworm Eisenia fetida

Y Li, X Wang, Z Sun - Journal of hazardous materials, 2020 - Elsevier
Petroleum is an important industrial raw material that enters the soil during production and
use and is harmful to soil organisms. To evaluate the toxicity of petroleum-contaminated soil …

The comet assay: past, present, and future

SAS Langie, A Azqueta, AR Collins - Frontiers in genetics, 2015 - frontiersin.org
The alkaline comet assay (single cell gel electrophoresis) is the most widely used method
for measuring DNA damage in eukaryotic cells (Neri et al., 2015). It detects strand breaks …

Comet assay: an essential tool in toxicological research

M Glei, T Schneider, W Schlörmann - Archives of toxicology, 2016 - Springer
The comet assay is a versatile, reliable, cost-efficient, and fast technique for detecting DNA
damage and repair in any tissue. It is useable in almost any cell type and applicable to both …

The next three decades of the comet assay: a report of the 11th International Comet Assay Workshop

G Koppen, A Azqueta, B Pourrut, G Brunborg… - …, 2017 - academic.oup.com
Abstract The International Comet Assay Workshops are a series of scientific conferences
dealing with practical and theoretical aspects of the Comet Assay (single-cell gel …

Studies on biomarkers of oxidative stress and associated genotoxicity and histopathology in Channa punctatus from heavy metal polluted canal

M Javed, I Ahmad, N Usmani, M Ahmad - Chemosphere, 2016 - Elsevier
Some investigations were made on the Satha canal water and health of dwelling fish
Channa punctatus at Satha village, district Aligarh (UP). Metal bioaccumulation and …

The comet assay in animal models: From bugs to whales–(Part 1 Invertebrates)

G Gajski, B Žegura, C Ladeira, B Pourrut… - … Research/Reviews in …, 2019 - Elsevier
The comet assay, also called single cell gel electrophoresis, is a sensitive, rapid and low-
cost technique for quantifying and analysing DNA damage and repair at the level of …