Mitochondrial heterogeneity
Cell-to-cell heterogeneity drives a range of (patho) physiologically important phenomena,
such as cell fate and chemotherapeutic resistance. The role of metabolism, and particularly …
such as cell fate and chemotherapeutic resistance. The role of metabolism, and particularly …
Evidence for host-dependent RNA editing in the transcriptome of SARS-CoV-2
The COVID-19 outbreak has become a global health risk, and understanding the response
of the host to the SARS-CoV-2 virus will help to combat the disease. RNA editing by host …
of the host to the SARS-CoV-2 virus will help to combat the disease. RNA editing by host …
Human mitochondrial RNA processing and modifications: overview
M Jedynak-Slyvka, A Jabczynska… - International Journal of …, 2021 - mdpi.com
Mitochondria, often referred to as the powerhouses of cells, are vital organelles that are
present in almost all eukaryotic organisms, including humans. They are the key energy …
present in almost all eukaryotic organisms, including humans. They are the key energy …
The m1A landscape on cytosolic and mitochondrial mRNA at single-base resolution
Modifications on mRNA offer the potential of regulating mRNA fate post-transcriptionally.
Recent studies suggested the widespread presence of N 1-methyladenosine (m1A), which …
Recent studies suggested the widespread presence of N 1-methyladenosine (m1A), which …
Lineage tracing in humans enabled by mitochondrial mutations and single-cell genomics
Lineage tracing provides key insights into the fate of individual cells in complex organisms.
Although effective genetic labeling approaches are available in model systems, in humans …
Although effective genetic labeling approaches are available in model systems, in humans …
Dissemination of scientific software with Galaxy ToolShed
The proliferation of web-based integrative analysis frameworks has enabled users to
perform complex analyses directly through the web. Unfortunately, it also revoked the …
perform complex analyses directly through the web. Unfortunately, it also revoked the …
Animal mitochondrial DNA as we do not know it: mt-genome organization and evolution in nonbilaterian lineages
Animal mitochondrial DNA (mtDNA) is commonly described as a small, circular molecule
that is conserved in size, gene content, and organization. Data collected in the last decade …
that is conserved in size, gene content, and organization. Data collected in the last decade …
Tissue-specific mtDNA abundance from exome data and its correlation with mitochondrial transcription, mass and respiratory activity
Eukaryotic cells contain a population of mitochondria, variable in number and shape, which
in turn contain multiple copies of a tiny compact genome (mtDNA) whose expression and …
in turn contain multiple copies of a tiny compact genome (mtDNA) whose expression and …
Mitochondrial 16S rRNA is methylated by tRNA methyltransferase TRMT61B in all vertebrates
The mitochondrial ribosome, which translates all mitochondrial DNA (mtDNA)-encoded
proteins, should be tightly regulated pre-and post-transcriptionally. Recently, we found RNA …
proteins, should be tightly regulated pre-and post-transcriptionally. Recently, we found RNA …
Cell reprogramming shapes the mitochondrial DNA landscape
Individual induced pluripotent stem cells (iPSCs) show considerable phenotypic
heterogeneity, but the reasons for this are not fully understood. Comprehensively analysing …
heterogeneity, but the reasons for this are not fully understood. Comprehensively analysing …