[HTML][HTML] Renal health improvement in diabetes through microbiome modulation of the gut–kidney axis with biotics: a systematic and narrative review of randomized …

P Paul, R Kaul, A Chaari - International Journal of Molecular Sciences, 2022 - mdpi.com
Diabetes mellitus is the most common endocrine disorder worldwide, with over 20% of
patients ultimately develo** diabetic kidney disease (DKD), a complex nephropathic …

[HTML][HTML] The Functions of SARS-CoV-2 Receptors in Diabetes-Related Severe COVID-19

A Drzymała - International Journal of Molecular Sciences, 2024 - mdpi.com
Angiotensin-converting enzyme 2 (ACE2) is considered a severe acute respiratory
syndrome coronavirus 2 (SARS-CoV-2) receptor of high importance, but due to its non …

Identification of serum metabolome signatures associated with retinal and renal complications of type 2 diabetes

Y Tomofuji, K Suzuki, T Kishikawa, N Shojima… - Communications …, 2023 - nature.com
Background Type 2 diabetes is a common disease around the world and its major
complications are diabetic retinopathy (DR) and diabetic kidney disease (DKD). Persons …

Neuraminidase inhibition improves endothelial function in diabetic mice

CA Foote, FI Ramirez-Perez, JA Smith… - American Journal …, 2023 - journals.physiology.org
Neuraminidases cleave sialic acids from glycocalyx structures and plasma neuraminidase
activity is elevated in type 2 diabetes (T2D). Therefore, we hypothesize circulating …

Sialic acid as a potential biomarker for cardiovascular disease, diabetes and cancer

J Cheeseman, G Kuhnle, G Stafford… - Biomarkers in …, 2021 - Taylor & Francis
Cardiovascular disease (CVD), diabetes and cancer pose increasing global healthcare
burdens. New biomarkers could enable earlier diagnosis of these diseases, leading to more …

The connections of sialic acids and diabetes mellitus: therapeutic or diagnostic value?

MA Ibrahim, MB Isah, MD Inim, AD Abdullahi… - …, 2024 - academic.oup.com
Modulation of sialic acids is one of the important pathological consequences of both type 1
and type 2 diabetes mellitus with or without the micro-and macrovascular complications …

[PDF][PDF] Sialic acid: an attractive biomarker with promising biomedical applications

A Doostkam, L Malekmakan, A Hosseinpour… - … research, reviews and …, 2022 - sciendo.com
This broad, narrative review highlights the roles of sialic acids as acidic sugars found on
cellular membranes. The role of sialic acids in cellular communication and development has …

[HTML][HTML] Metformin attenuates adhesion between cancer and endothelial cells in chronic hyperglycemia by recovery of the endothelial glycocalyx barrier

M Targosz-Korecka, KE Malek-Zietek, D Kloska… - … et Biophysica Acta (BBA …, 2020 - Elsevier
Background Epidemiologic studies suggest that diabetes is associated with an increased
risk of cancer. Concurrently, clinical trials have shown that metformin, which is a first-line …

Combined untargeted and targeted metabolomics approaches reveal urinary changes of amino acids and energy metabolism in canine babesiosis with different …

J Kuleš, I Rubić, B Beer Ljubić, P Bilić… - Frontiers in …, 2021 - frontiersin.org
Canine babesiosis is a tick-borne disease with a worldwide distribution, caused by the
haemoprotozoan parasites of the genus Babesia. One of the most prevalent complication is …

Desialylation is associated with apoptosis and phagocytosis of platelets in patients with prolonged isolated thrombocytopenia after allo-HSCT

XH Zhang, QM Wang, JM Zhang, FE Feng… - Journal of hematology & …, 2015 - Springer
Background Prolonged isolated thrombocytopenia (PT) is a frequent complication in patients
who undergo allogeneic hematopoietic stem cell transplantation (allo-HSCT), and it is …