Biosensors are of great significance because of their capability to resolve a potentially large
number of analytical problems and challenges in very diverse areas such as defense …

Aptamers, including DNA, RNA and peptide aptamers, are a group of promising recognition
units that can specifically bind to target molecules and cells. Due to their excellent specificity …

Aptamers are single-stranded DNA or RNA oligomers that have the ability to generate
unique and diverse tertiary structures that bind to cognate molecules with high specificity. In …

Progress in cell purification technology is critical to increase the availability of viable cells for
therapeutic, diagnostic, and research applications. A variety of techniques are now available …

Since aptamer and its in vitro selection process called SELEX were independently
described by Ellington and Gold in 1990, extensive research has been undertaken and …

The analysis of circulating tumor cells (CTCs) holds great significance for cancer diagnosis,
prognosis, and personalized therapy. However, the rarity, vulnerability and heterogeneity of …

Aptamer-functionalized materials (AFMs) are promising specific recognition materials in
sample-preparation techniques due to the inherently high affinity and selectivity associated …

Detection of rare circulating tumor cells (CTCs) in peripheral blood is a challenging, but
necessary, task in order to diagnose early onset of metastatic cancer and to monitor …

Abstract Structure-switching aptamer-based biosensors (aptasensors) provide a promising
strategy for real-time or near real-time monitoring of analytes in vivo, owing to their …

Aptamers are high affinity single-stranded nucleic acid or protein ligands which exhibit
specificity and avidity comparable to, or exceeding that of antibodies and can be generated …