Current advance of nanotechnology in diagnosis and treatment for malignant tumors
Cancer remains a significant risk to human health. Nanomedicine is a new multidisciplinary
field that is garnering a lot of interest and investigation. Nanomedicine shows great potential …
field that is garnering a lot of interest and investigation. Nanomedicine shows great potential …
Extracellular vesicles: a rising star for therapeutics and drug delivery
S Du, Y Guan, A **e, Z Yan, S Gao, W Li, L Rao… - Journal of …, 2023 - Springer
Extracellular vesicles (EVs) are nano-sized, natural, cell-derived vesicles that contain the
same nucleic acids, proteins, and lipids as their source cells. Thus, they can serve as natural …
same nucleic acids, proteins, and lipids as their source cells. Thus, they can serve as natural …
Three 'E'challenges for siRNA drug development
siRNA therapeutics have gained extensive attention, and to date six siRNAs are approved
for clinical use. Despite being investigated for the treatment of metabolic, cardiovascular …
for clinical use. Despite being investigated for the treatment of metabolic, cardiovascular …
[HTML][HTML] NK cell-based tumor immunotherapy
H Zhang, L Yang, T Wang, Z Li - Bioactive materials, 2024 - Elsevier
Natural killer (NK) cells display a unique inherent ability to identify and eliminate virus-
infected cells and tumor cells. They are particularly powerful for elimination of hematological …
infected cells and tumor cells. They are particularly powerful for elimination of hematological …
A Curcumin‐Modified Coordination Polymers with ROS Scavenging and Macrophage Phenotype Regulating Properties for Efficient Ulcerative Colitis Treatment
H Yao, F Wang, H Chong, J Wang, Y Bai… - Advanced …, 2023 - Wiley Online Library
Overexpression of classically activated macrophages (M1) subtypes and assessed reactive
oxygen species (ROS) levels are often observed in patients with ulcerative colitis. At present …
oxygen species (ROS) levels are often observed in patients with ulcerative colitis. At present …
Cold nanozyme for precise enzymatic antitumor immunity
Y Zou, B **, H Li, X Wu, Y Liu, H Zhao, D Zhong… - ACS …, 2022 - ACS Publications
Precise catalysis is pursued for the biomedical applications of artificial enzymes. It is feasible
to precisely control the catalysis of artificial enzymes via tunning the temperature-dependent …
to precisely control the catalysis of artificial enzymes via tunning the temperature-dependent …
Exosome membrane-coated nanosystems: Exploring biomedical applications in cancer diagnosis and therapy
Bio-mimicking principles have recently been proposed for the surface functionalization of
nanoparticles (NPs). Such a strategy is based on camouflaging the NP surface with …
nanoparticles (NPs). Such a strategy is based on camouflaging the NP surface with …
Intracellularly Synthesized Artificial Exosome Treats Acute Lung Injury
L Liang, W Peng, A Qin, J Zhang, R Chen, D Zhou… - ACS …, 2024 - ACS Publications
Acute lung injury (ALI) and its severe form, acute respiratory distress syndrome (ARDS),
induce high morbidity and mortality rates, which challenge the present approaches for the …
induce high morbidity and mortality rates, which challenge the present approaches for the …
[HTML][HTML] Platelet-derived extracellular vesicles ameliorate intervertebral disc degeneration by alleviating mitochondrial dysfunction
Z Dai, C **a, T Zhao, H Wang, H Tian, O Xu, X Zhu… - Materials Today Bio, 2023 - Elsevier
Mitochondrial dysfunction causes the production of reactive oxygen species (ROS) and
oxidative damage, and oxidative stress and inflammation are considered key factors causing …
oxidative damage, and oxidative stress and inflammation are considered key factors causing …
CRISPR/Cas9 and chlorophyll coordination micelles for cancer treatment by genome editing and photodynamic therapy
C Zhang, X Wang, G Liu, H Ren, J Liu, Z Jiang… - Small, 2023 - Wiley Online Library
CRISPR/Cas9‐based gene therapy and photodynamic therapy both show promise for
cancer treatment but still have their drawbacks limited by tumor microenvironment and long …
cancer treatment but still have their drawbacks limited by tumor microenvironment and long …