Animal models to improve our understanding and treatment of suicidal behavior
Worldwide, suicide is a leading cause of death. Although a sizable proportion of deaths by
suicide may be preventable, it is well documented that despite major governmental and …
suicide may be preventable, it is well documented that despite major governmental and …
Alterations in gene expression due to chronic lead exposure induce behavioral changes
A Hernandez-Coro, BE Sánchez-Hernández… - Neuroscience & …, 2021 - Elsevier
Lead (Pb) is a pollutant commonly found in the environment, despite the implementation of
public health policies intended to remove it. Due to its chemical characteristics as a divalent …
public health policies intended to remove it. Due to its chemical characteristics as a divalent …
RVG29-modified microRNA-loaded nanoparticles improve ischemic brain injury by nasal delivery
R Hao, B Sun, L Yang, C Ma, S Li - Drug Delivery, 2020 - Taylor & Francis
Effective nose-to-brain delivery needs to be developed to treat neurodegenerative diseases.
Regulating miR-124 can effectively improve the symptoms of ischemic brain injury and …
Regulating miR-124 can effectively improve the symptoms of ischemic brain injury and …
MicroRNA‑124: an emerging therapeutic target in central nervous system disorders
WH Zhang, L Jiang, M Li, J Liu - Experimental Brain Research, 2023 - Springer
The central nervous system (CNS) consists of neuron and non-neuron cells including neural
stem/precursor cells (NSPCs), neuroblasts, glia cells (mainly astrocyte, oligodendroglia and …
stem/precursor cells (NSPCs), neuroblasts, glia cells (mainly astrocyte, oligodendroglia and …
Genome‐wide analyses of aggressiveness in attention‐deficit hyperactivity disorder
EJ Brevik, MMJ van Donkelaar, H Weber… - American Journal of …, 2016 - Wiley Online Library
Aggressiveness is a behavioral trait that has the potential to be harmful to individuals and
society. With an estimated heritability of about 40%, genetics is important in its development …
society. With an estimated heritability of about 40%, genetics is important in its development …
Modeling endophenotypes of suicidal behavior in animals
B Roy, Y Dwivedi - Neuroscience & Biobehavioral Reviews, 2021 - Elsevier
Suicide is a major public health concern. One of the common contributors to the increased
risk for suicide is the genetic constitution of individuals, which determines certain …
risk for suicide is the genetic constitution of individuals, which determines certain …
[HTML][HTML] A functional polymorphism in the DRD1 gene, that modulates its regulation by miR-504, is associated with depressive symptoms
KM Jiménez, AJ Pereira-Morales… - Psychiatry …, 2018 - ncbi.nlm.nih.gov
Objective The aim of this study was to examine a possible association between depressive
symptoms and a functional polymorphism (rs686) that modulates the regulation of DRD1 …
symptoms and a functional polymorphism (rs686) that modulates the regulation of DRD1 …
Epigenetics of aggressive behavior
RN Mustafin, AV Kazantseva, RF Enikeeva… - Russian Journal of …, 2019 - Springer
Multiple studies demonstrating the association of aggressive behavior with allelic variants of
neurotransmitter system genes appear to be controversial, while “risk” alleles have no effect …
neurotransmitter system genes appear to be controversial, while “risk” alleles have no effect …
Analysis of the association of MIR124-1 and its target gene RGS4 polymorphisms with major depressive disorder and antidepressant response
D Zeng, S He, S Yu, G Li, C Ma, Y Wen… - Neuropsychiatric …, 2018 - Taylor & Francis
Background Increasing evidence has indicated that dysfunction of miR-124 and target gene
regulator of G protein signaling 4 (RGS4) may be involved in the etiology and treatment of …
regulator of G protein signaling 4 (RGS4) may be involved in the etiology and treatment of …
Network and Pathway-Based Integrated Analysis Identified a Novel “rs28457673–miR-15/16/195/424/497 Family–IGF1R–MAPK Signaling Pathway” Axis Associated …
Y Li, Z Wang, M Zhu, G Fan, G Xu, T Zhao… - Frontiers in Cell and …, 2021 - frontiersin.org
Single-nucleotide polymorphisms (SNPs) of microRNA (miRNA)(miRSNP) are SNPs located
on miRNA genes or miRNA target sites, which have been supposed to be involved in the …
on miRNA genes or miRNA target sites, which have been supposed to be involved in the …