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The role of DNA damage repair (DDR) system in response to immune checkpoint inhibitor (ICI) therapy
As our understanding of the mechanisms of cancer treatment has increased, a growing
number of studies demonstrate pathways through which DNA damage repair (DDR) affects …
number of studies demonstrate pathways through which DNA damage repair (DDR) affects …
Anticancer potential of phytochemicals derived from mangrove plants: Comprehensive mechanistic insights
Cancer is a collection of illnesses characterized by aberrant cellular proliferation that can
infiltrate or metastasize to distant anatomical sites, posing a notable threat to human well …
infiltrate or metastasize to distant anatomical sites, posing a notable threat to human well …
Apigeninidin-enriched Sorghum bicolor (L. Moench) extracts alleviate Aflatoxin B1-induced dysregulation of male rat hypothalamic-reproductive axis
We examined the protective effect of the apigeninidin (API)-enriched fraction from Sorghum
bicolor sheaths extracts (SBE-05, SBE-06, and SBE-07) against aflatoxin B1 (AFB1)-induced …
bicolor sheaths extracts (SBE-05, SBE-06, and SBE-07) against aflatoxin B1 (AFB1)-induced …
Bacterial immunotherapy: is it a weapon in our arsenal in the fight against cancer?
Advances in understanding the genetic basis of cancer have driven alternative treatment
approaches. Recent findings have demonstrated the potential of bacteria and it's …
approaches. Recent findings have demonstrated the potential of bacteria and it's …
[HTML][HTML] Therapeutic strategies to enhance Tumor Antigenicity: making the Tumor detectable by the Immune System
D Meraviglia-Crivelli, A Zheleva, M Barainka, B Moreno… - Biomedicines, 2022 - mdpi.com
Cancer immunotherapy has revolutionized the oncology field, but many patients still do not
respond to current immunotherapy approaches. One of the main challenges in broadening …
respond to current immunotherapy approaches. One of the main challenges in broadening …
Sodium‐Glucose Co‐Transporter‐2 Inhibitor Empagliflozin Attenuates Sorafenib‐Induced Myocardial Inflammation and Toxicity
CH Liu, YC Ho, WC Lee, CY Huang… - Environmental …, 2024 - Wiley Online Library
Environmental antineoplastics such as sorafenib may pose a risk to humans through water
recycling, and the increased risk of cardiotoxicity is a clinical issue in sorafenib users. Thus …
recycling, and the increased risk of cardiotoxicity is a clinical issue in sorafenib users. Thus …
Genes and the environment in cancer: focus on environmentally induced DNA methylation changes
F Coppedè - Cancers, 2023 - mdpi.com
Cancer has traditionally been viewed as a genetic disorder resulting from the accumulation
of gene mutations, chromosomal rearrangements, and aneuploidies in somatic cells …
of gene mutations, chromosomal rearrangements, and aneuploidies in somatic cells …
Exploring the Role of Clustered Mutations in Carcinogenesis and Their Potential Clinical Implications in Cancer
Y Li, R Zhu, J **, H Guo, J Zhang, Z He… - International Journal of …, 2024 - mdpi.com
Abnormal cell proliferation and growth leading to cancer primarily result from cumulative
genome mutations. Single gene mutations alone do not fully explain cancer onset and …
genome mutations. Single gene mutations alone do not fully explain cancer onset and …
Multi-Endpoint Toxicological Assessment of Chrysin Loaded Oil-in-Water Emulsion System in Different Biological Models
P Pitchakarn, P Ting, P Buacheen, J Karinchai… - Nanomaterials, 2024 - mdpi.com
Chrysin is hypothesized to possess the ability to prevent different illnesses, such as
diabetes, cancer, and neurodegenerative disorders. Nonetheless, chrysin has a low …
diabetes, cancer, and neurodegenerative disorders. Nonetheless, chrysin has a low …
Molecular dynamics of DNA repair and carcinogen interaction: Implications for cancer initiation, progression, and therapeutic strategies
The integrity of the genetic material in human cells is continuously challenged by
environmental agents and endogenous stresses. Among these, environmental carcinogens …
environmental agents and endogenous stresses. Among these, environmental carcinogens …