Background The brain is a highly mechanosensitive organ, and changes in the mechanical
properties of brain tissue influence many physiological and pathological processes. Piezo …

Thrombus composition and mechanical properties significantly impact the ease and
outcomes of thrombectomy procedures in patients with acute ischemic stroke. A wide …

Objective In the real-world practice of endovascular thrombectomy (EVT) for acute ischemic
stroke (AIS), the analysis of intraprocedural angiographic signs (IPASs) still challenges …

BACKGROUND AND PURPOSE: Previous studies have successfully created blood clot
analogs for in vitro endovascular device testing using animal blood of various species …

In-vitro neurovascular models of large vessel occlusions (LVOs) causing acute ischemic
stroke (AIS) are used extensively for pre-clinical testing of new treatment devices. They …

Arterial occlusion by thrombosis is the immediate cause of some strokes, heart attacks, and
peripheral artery disease. Most prior studies assume that coagulation creates the thrombus …

Preclinical testing platforms have been instrumental in the research and development of
thrombectomy devices. However, there is no single model which fully captures the …

OBJECTIVE Despite advancement of thrombectomy technologies for large-vessel occlusion
(LVO) stroke and increased user experience, complete recanalization rates linger around …

BACKGROUND AND PURPOSE: Aspiration thrombectomy has become a preferred
approach to recanalize large-vessel occlusion in stroke with a growing trend toward using …

BACKGROUND Appropriate thrombus-device interaction is critical for recanalization.
Histology can serve as a proxy for mechanical properties, and thus inform technique …