Inhaled sargramostim (recombinant human granulocyte-macrophage colony-stimulating factor) for COVID-19-associated acute hypoxemia: results of the phase 2 …

R Paine, R Chasse, ES Halstead, J Nfonoyim… - Military …, 2023 - academic.oup.com
Introduction Granulocyte-macrophage colony-stimulating factor (GM-CSF), a protein
produced in the lung, is essential for pulmonary host defense and alveolar integrity. Prior …

Pulmonary function and Quality of Life in a prospective cohort of (non-) hospitalized COVID-19 pneumonia survivors up to six months

MP de Roos, S Siegerink, NG Dijkstra… - Chronic respiratory …, 2022 - journals.sagepub.com
Objectives A decrease of both diffusion capacity (DLCO) and Quality of Life (QoL) was
reported after discharge in hospitalized COVID-19 pneumonia survivors. We studied three …

Alveolar arterial gradient and respiratory index in predicting the outcome of COVID-19 patients; a retrospective cross-sectional study

A Singh, KD Soni, Y Singh, R Aggarwal… - Archives of …, 2022 - pmc.ncbi.nlm.nih.gov
Introduction: Alveolar arterial (Aa) oxygen gradient and respiratory index can be of immense
help for the critical care physician in clinical decision making. This study aimed to evaluate …

[HTML][HTML] Alveolar–Arterial Gradient Is an Early Marker to Predict Severe Pneumonia in COVID-19 Patients

G Pipitone, M Camici, G Granata, A Sanfilippo… - Infectious Disease …, 2022 - mdpi.com
Background: One of the main challenges in the management of COVID-19 patients is to
early assess and stratify them according to their risk of develo** severe pneumonia. The …

Oxygenation indices and early prediction of outcome in hypoxemic patients with COVID-19 pneumonia requiring noninvasive respiratory support in pulmonary …

R Scala, T Renda, S Bambina, L Guidelli, S Arniani… - Pneumonia, 2024 - Springer
Background Early prediction of non-invasive respiratory therapy (NIRT) failure is crucial to
avoid needless prolongation of respiratory support and delayed endotracheal intubation …

Trajectory of the arterial-alveolar oxygen gradient in COPD for a decade

K Nagata, S Sato, K Uemasu, N Tanabe, A Sato… - PloS one, 2025 - journals.plos.org
Background Chronic respiratory failure (CRF) is a critical complication in patients with
chronic obstructive pulmonary disease (COPD) and is characterized by an increase in the …

[HTML][HTML] Frequency and spectrum of incidental findings when using chest CT as a primary triage tool for COVID-19

ID Kilsdonk, MP de Roos, P Bresser, HJ Reesink… - European journal of …, 2021 - Elsevier
Purpose To determine the prevalence and spectrum of incidental findings (IFs) identified in
patients undergoing chest CT as a primary triage tool for COVID-19. Methods In this study …

The Association Between Alveolar–Arterial Oxygen Tension Difference and the Severity of COVID-19 in Patients

C **e, J Deng, F Li, C Wu, M Xu, B Yu, G Wu… - Infectious Diseases and …, 2023 - Springer
Abstract Introduction Coronavirus disease 2019 (COVID-19) emerged as a global pandemic
and resulted in a significantly high death toll. Therefore, there is an urgent need to find a …

Comparison of positive pressure extubation with traditional extubation in critically ill patients–a randomised control study

AT Prabhakaran, D Vanalal, K Soni, D Baidya… - Anaesthesiology …, 2023 - termedia.pl
Background: Two extubation methods are commonly used in the intensive care unit (ICU):
the traditional method with endotracheal suctioning and the positive-pressure method …

[HTML][HTML] Alveolar-arterial oxygen gradient: An early marker to predict the severity of community-acquired pneumonia in children

B Zhao, M Si, Z Hu, J Jiang - Medicine, 2024 - journals.lww.com
To study the clinical significance of alveolar-arterial oxygen gradient (P Aa O 2) for children
with community-acquired pneumonia (CAP). A prospective study was carried out from …