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Formation and function of multiciliated cells
Q Lyu, Q Li, J Zhou, H Zhao - Journal of Cell Biology, 2024 - rupress.org
In vertebrates, multiciliated cells (MCCs) are terminally differentiated cells that line the
airway tracts, brain ventricles, and reproductive ducts. Each MCC contains dozens to …
airway tracts, brain ventricles, and reproductive ducts. Each MCC contains dozens to …
The multifaceted roles of microtubule-associated proteins in the primary cilium and ciliopathies
J Deretic, E Odabasi… - Journal of Cell …, 2023 - journals.biologists.com
The primary cilium is a conserved microtubule-based organelle that is critical for transducing
developmental, sensory and homeostatic signaling pathways. It comprises an axoneme with …
developmental, sensory and homeostatic signaling pathways. It comprises an axoneme with …
EHD1 promotes CP110 ubiquitination by centriolar satellite delivery of HERC2 to the mother centriole
Primary cilia are sensory organelles that coordinate diverse signaling pathways, controlling
development and homeostasis. Progression beyond the early steps of ciliogenesis requires …
development and homeostasis. Progression beyond the early steps of ciliogenesis requires …
Regulation of epidermal stratification and development by basal keratinocytes
H Yin, M Hu, D Li - Journal of cellular physiology, 2023 - Wiley Online Library
The epidermis is a stratified squamous epithelium distributed in the outermost layer of the
skin and is intimately involved in the formation of a physical barrier to pathogens. Basal …
skin and is intimately involved in the formation of a physical barrier to pathogens. Basal …
[HTML][HTML] Peripheral and central control of obesity by primary cilia
Y Wu, J Zhou, Y Yang - Journal of Genetics and Genomics, 2023 - Elsevier
Primary cilia are hair-like structures that protrude from the cell surface. They are capable of
sensing external cues and conveying a vast array of signals into cells to regulate a variety of …
sensing external cues and conveying a vast array of signals into cells to regulate a variety of …
Emerging insights into CP110 removal during early steps of ciliogenesis
The primary cilium is an antenna-like projection from the plasma membrane that serves as a
sensor of the extracellular environment and a crucial signaling hub. Primary cilia are …
sensor of the extracellular environment and a crucial signaling hub. Primary cilia are …
Cytoskeletal networks in primary cilia: Current knowledge and perspectives
R Ge, M Cao, M Chen, M Liu… - Journal of Cellular …, 2022 - Wiley Online Library
Primary cilia, microtubule‐based protrusions present on the surface of most mammalian
cells, function as sensory organelles that monitor extracellular signals and transduce them …
cells, function as sensory organelles that monitor extracellular signals and transduce them …
CYLD Maintains Retinal Homeostasis by Deubiquitinating ENKD1 and Promoting the Phagocytosis of Photoreceptor Outer Segments
S Yang, F Yu, M Yang, H Ni, W Bu, H Yin… - Advanced …, 2024 - Wiley Online Library
Phagocytosis of shed photoreceptor outer segments by the retinal pigment epithelium (RPE)
is essential for retinal homeostasis. Dysregulation of the phagocytotic process is associated …
is essential for retinal homeostasis. Dysregulation of the phagocytotic process is associated …
Primary cilium‐mediated signaling cascade suppresses age‐related biliary fibrosis
R Hong, X Tian, H Ma, H Ni, J Yang… - Journal of Cellular …, 2023 - Wiley Online Library
The primary cilium is increasingly recognized as a crucial player in the physiology of biliary
epithelial cells (BECs). However, the precise role of primary cilia in the development of age …
epithelial cells (BECs). However, the precise role of primary cilia in the development of age …
Melanocortin 1 receptor mediates melanin production by interacting with the BBSome in primary cilia
X Tian, H Wang, S Liu, W Liu, K Zhang, X Gao, Q Li… - PLoS …, 2024 - journals.plos.org
Production of melanin pigments is a protective mechanism of the skin against ultraviolet
(UV)-induced damage and carcinogenesis. However, the molecular basis for …
(UV)-induced damage and carcinogenesis. However, the molecular basis for …