[HTML][HTML] Brain-spleen axis in health and diseases: A review and future perspective
The spleen, an important tissue for the immune system, acts as a filter for blood within the
immune system. Accumulating evidence suggests that the spleen affects a number of brain …
immune system. Accumulating evidence suggests that the spleen affects a number of brain …
The impact of acute and chronic stress on gastrointestinal physiology and function: a microbiota–gut–brain axis perspective
The physiological consequences of stress often manifest in the gastrointestinal tract.
Traumatic or chronic stress is associated with widespread maladaptive changes throughout …
Traumatic or chronic stress is associated with widespread maladaptive changes throughout …
The impact of chronic stress on energy metabolism
MA van der Kooij - Molecular and Cellular Neuroscience, 2020 - Elsevier
The brain is exceptionally demanding in terms of energy metabolism. Approximately 20% of
the calories consumed are devoted to our cerebral faculties, with the lion's share provided in …
the calories consumed are devoted to our cerebral faculties, with the lion's share provided in …
The intersection between ghrelin, metabolism and circadian rhythms
Despite the growing popular interest in sleep and diet, many gaps exist in our scientific
understanding of the interaction between circadian rhythms and metabolism. In this Review …
understanding of the interaction between circadian rhythms and metabolism. In this Review …
The effects of sleep disruption on metabolism, hunger, and satiety, and the influence of psychosocial stress and exercise: A narrative review
Sleep deficiency is a ubiquitous phenomenon among Americans. In fact, in the United
States,∼ 78% of teens and 35% of adults currently get less sleep than recommended for …
States,∼ 78% of teens and 35% of adults currently get less sleep than recommended for …
Ghrelin as a stress hormone: implications for psychiatric illness
The stress response is an adaptive means of maintaining physiological homeostasis in the
face of changing environmental conditions. However, protracted recruitment of stress …
face of changing environmental conditions. However, protracted recruitment of stress …
Ghrelin receptor signaling in health and disease: a biased view
As allosteric complexes, G-protein-coupled receptors (GPCRs) respond to extracellular
stimuli and pleiotropically couple to intracellular transducers to elicit signaling pathway …
stimuli and pleiotropically couple to intracellular transducers to elicit signaling pathway …
The intriguing ligand-dependent and ligand-independent actions of the growth hormone secretagogue receptor on reward-related behaviors
The growth hormone secretagogue receptor (GHSR) is a G-protein-coupled receptor
(GPCR) highly expressed in the brain, and also in some peripheral tissues. GHSR activity is …
(GPCR) highly expressed in the brain, and also in some peripheral tissues. GHSR activity is …
The good, the bad and the unknown aspects of ghrelin in stress co** and stress-related psychiatric disorders
EM Fritz, N Singewald, D De Bundel - Frontiers in synaptic …, 2020 - frontiersin.org
Ghrelin is a peptide hormone released by specialized X/A cells in the stomach and activated
by acylation. Following its secretion, it binds to ghrelin receptors in the periphery to regulate …
by acylation. Following its secretion, it binds to ghrelin receptors in the periphery to regulate …
GHSR blockade, but not reduction of peripherally circulating ghrelin via β1-adrenergic receptor antagonism, decreases binge-like alcohol drinking in mice
RS Richardson, LA Kryszak, JCM Vendruscolo… - Molecular …, 2024 - nature.com
Alcohol use disorder (AUD) and binge drinking are highly prevalent public health issues.
The stomach-derived peptide ghrelin, and its receptor, the growth hormone secretagogue …
The stomach-derived peptide ghrelin, and its receptor, the growth hormone secretagogue …