Pathogenicity and virulence of Staphylococcus aureus

GYC Cheung, JS Bae, M Otto - Virulence, 2021 - Taylor & Francis
Staphylococcus aureus is one of the most frequent worldwide causes of morbidity and
mortality due to an infectious agent. This pathogen can cause a wide variety of diseases …

Bacterial quorum sensing: its role in virulence and possibilities for its control

ST Rutherford, BL Bassler - Cold Spring …, 2012 - perspectivesinmedicine.cshlp.org
Quorum sensing is a process of cell–cell communication that allows bacteria to share
information about cell density and adjust gene expression accordingly. This process …

Regulation of Staphylococcus aureus Virulence

C Jenul, AR Horswill - Microbiology spectrum, 2019 - Am Soc Microbiol
Staphylococcus aureus is a Gram-positive opportunistic pathogen that has evolved a
complex regulatory network to control virulence. One of the main functions of this …

Whole genome sequencing of meticillin-resistant Staphylococcus aureus

M Kuroda, T Ohta, I Uchiyama, T Baba, H Yuzawa… - The Lancet, 2001 - thelancet.com
Background Staphylococcus aureus is one of the major causes of community-acquired and
hospital-acquired infections. It produces numerous toxins including superantigens that …

Targeting the holy triangle of quorum sensing, biofilm formation, and antibiotic resistance in pathogenic bacteria

RV Sionov, D Steinberg - Microorganisms, 2022 - mdpi.com
Chronic and recurrent bacterial infections are frequently associated with the formation of
biofilms on biotic or abiotic materials that are composed of mono-or multi-species cultures of …

Autoinduction and signal transduction in the regulation of staphylococcal virulence

RP Novick - Molecular microbiology, 2003 - Wiley Online Library
The accessory genes of Staphylococcus aureus, in‐cluding those involved in pathogenesis,
are controlled by a complex regulatory network that includes at least four two‐component …

Quorum-sensing regulation in staphylococci—an overview

KY Le, M Otto - Frontiers in microbiology, 2015 - frontiersin.org
Staphylococci are frequent human commensals and some species can cause disease.
Staphylococcus aureus in particular is a dangerous human pathogen. In staphylococci, the …

Quorum sensing in staphylococci

RP Novick, E Geisinger - Annual review of genetics, 2008 - annualreviews.org
The staphylococcal agr locus encodes a quorum sensing (QS) system that controls the
expression of virulence and other accessory genes by a classical two-component signaling …

Staphylococcal and streptococcal superantigen exotoxins

AR Spaulding, W Salgado-Pabón… - Clinical microbiology …, 2013 - Am Soc Microbiol
This review begins with a discussion of the large family of Staphylococcus aureus and beta-
hemolytic streptococcal pyrogenic toxin T lymphocyte superantigens from structural and …

Basis of virulence in enterotoxin-mediated staphylococcal food poisoning

EL Fisher, M Otto, GYC Cheung - Frontiers in microbiology, 2018 - frontiersin.org
The Staphylococcus aureus enterotoxins are a superfamily of secreted virulence factors that
share structural and functional similarities and possess potent superantigenic activity …