Experimental manipulation of microbiota reduces host thermal tolerance and fitness under heat stress in a vertebrate ectotherm

SS Fontaine, PM Mineo, KD Kohl - Nature Ecology & Evolution, 2022 - nature.com
Identifying factors that influence how ectothermic animals respond physiologically to
changing temperatures is of high importance given current threats of global climate change …

Pooled biological specimens for human biomonitoring of environmental chemicals: opportunities and limitations

AL Heffernan, LL Aylward, LML Toms, PD Sly… - Journal of exposure …, 2014 - nature.com
Biomonitoring has become the “gold standard” in assessing chemical exposures, and has
an important role in risk assessment. The pooling of biological specimens—combining …

Age as a determinant of phosphate flame retardant exposure of the Australian population and identification of novel urinary PFR metabolites

N Van den Eede, AL Heffernan, LL Aylward… - Environment …, 2015 - Elsevier
The demand for alternative flame retardant materials such as phosphate flame retardants
and plasticizers (PFRs) is increasing, although little is known of their possible effects on …

Experimental validation of methods for differential gene expression analysis and sample pooling in RNA-seq

AP Rajkumar, P Qvist, R Lazarus, F Lescai, J Ju… - BMC genomics, 2015 - Springer
Background Massively parallel cDNA sequencing (RNA-seq) experiments are gradually
superseding microarrays in quantitative gene expression profiling. However, many …

Use of pooled samples to assess human exposure to parabens, benzophenone-3 and triclosan in Queensland, Australia

AL Heffernan, C Baduel, LML Toms, AM Calafat… - Environment …, 2015 - Elsevier
Parabens, benzophenone-3 and triclosan are common ingredients used as preservatives,
ultraviolet radiation filters and antimicrobial agents, respectively. Human exposure occurs …

[HTML][HTML] Towards guidelines for time-trend reviews examining temporal variability in human biomonitoring data of pollutants

BM Sharma, J Kalina, P Whaley, M Scheringer - Environment International, 2021 - Elsevier
In the last few decades, a plethora of studies have focused on human biomonitoring (HBM)
of chemical pollutants. Reviewing the copious HBM data reported in these studies is …

Investigating sample pooling strategies for DIGE experiments to address biological variability

NA Karp, KS Lilley - Proteomics, 2009 - Wiley Online Library
If biological questions are to be answered using quantitative proteomics, it is essential to
design experiments which have sufficient power to be able to detect changes in expression …

Key regulatory molecules of cartilage destruction in rheumatoid arthritis: an in vitrostudy

K Andreas, C Lübke, T Häupl, T Dehne… - Arthritis research & …, 2008 - Springer
Background Rheumatoid arthritis (RA) is a chronic, inflammatory and systemic autoimmune
disease that leads to progressive cartilage destruction. Advances in the treatment of RA …

Monitoring exposure to polycyclic aromatic hydrocarbons in an Australian population using pooled urine samples

PK Thai, AL Heffernan, LML Toms, Z Li… - Environment …, 2016 - Elsevier
Integrated exposure to polycyclic aromatic hydrocarbons (PAHs) can be assessed through
monitoring of urinary mono-hydroxylated PAHs (OH-PAHs). The aim of this study was to …

[BOOK][B] Gene expression studies using Affymetrix microarrays

H Gohlmann, W Talloen - 2009 - taylorfrancis.com
The Affymetrix GeneChip system is one of the most widely adapted microarray platforms.
However, due to the overwhelming amount of information available, many Affymetrix users …