A comprehensive analysis and anti-cancer activities of quercetin in ROS-mediated cancer and cancer stem cells
Reactive oxygen species (ROS) induce carcinogenesis by causing genetic mutations,
activating oncogenes, and increasing oxidative stress, all of which affect cell proliferation …
activating oncogenes, and increasing oxidative stress, all of which affect cell proliferation …
The efficacy of natural bioactive compounds against prostate cancer: Molecular targets and synergistic activities
Globally, prostate cancer (PCa) is regarded as a challenging health issue, and the number
of PCa patients continues to rise despite the availability of effective treatments in recent …
of PCa patients continues to rise despite the availability of effective treatments in recent …
Exploring the anti‐cancer potential of dietary phytochemicals for the patients with breast cancer: a comprehensive review
Background The most common and deadly cancer in female is breast cancer (BC) and new
incidence and deaths related to this cancer are rising. Aims Several issues, that is, high cost …
incidence and deaths related to this cancer are rising. Aims Several issues, that is, high cost …
Oxidative stress inducers in cancer therapy: Preclinical and clinical evidence
Reactive oxygen species (ROS) are metabolic byproducts that regulate various cellular
processes. However, at high levels, ROS induce oxidative stress, which in turn can trigger …
processes. However, at high levels, ROS induce oxidative stress, which in turn can trigger …
Study of MDM2 as Prognostic Biomarker in Brain-LGG Cancer and Bioactive Phytochemicals Inhibit the p53-MDM2 Pathway: A Computational Drug Development …
An evaluation of the expression and predictive significance of the MDM2 gene in brain lower-
grade glioma (LGG) cancer was carried out using onco-informatics pipelines. Several …
grade glioma (LGG) cancer was carried out using onco-informatics pipelines. Several …
Molecular Dynamics Simulation and Pharmacoinformatic Integrated Analysis of Bioactive Phytochemicals from Azadirachta indica (Neem) to Treat Diabetes Mellitus
Diabetes mellitus is a chronic hormonal and metabolic disorder in which our body cannot
generate necessary insulin or does not act in response to it, accordingly, ensuing in …
generate necessary insulin or does not act in response to it, accordingly, ensuing in …
New techniques and strategies in drug discovery (2020–2024 update)
Q Gong, J Song, Y Song, K Tang, P Yang… - Chinese Chemical …, 2024 - Elsevier
In the realm of drug discovery, recent advancements have paved the way for innovative
approaches and methodologies. This comprehensive review encapsulates six distinct yet …
approaches and methodologies. This comprehensive review encapsulates six distinct yet …
Profiling of antioxidant properties and identification of potential analgesic inhibitory activities of Allophylus villosus and Mycetia sinensis employing in vivo, in vitro, and …
Ethnopharmacological relevance The traditional use of plants for medicinal purposes, called
phytomedicine, has been known to provide relief from pain. In Bangladesh, the Chakma …
phytomedicine, has been known to provide relief from pain. In Bangladesh, the Chakma …
Drug repurposing and systems biology approaches of Enzastaurin can target potential biomarkers and critical pathways in colorectal Cancer
Colorectal cancer (CRC) is a severe health concern that results from a cocktail of genetic,
epigenetic, and environmental abnormalities. Because it is the second most lethal …
epigenetic, and environmental abnormalities. Because it is the second most lethal …
[HTML][HTML] Phyllanthus emblica (Amla) methanolic extract regulates multiple checkpoints in 15-lipoxygenase mediated inflammopathies: Computational simulation and in …
Amla (Phyllanthus emblica) has long been used in traditional folk medicine to prevent and
cure a variety of inflammatory diseases. In this study, the antioxidant activity (DPPH …
cure a variety of inflammatory diseases. In this study, the antioxidant activity (DPPH …