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Transformations of modified morita‐baylis‐hillman adducts from isatins catalyzed by lewis bases
The development of synthetic protocols to access architectures with broad structural and
functional diversity from readily available starting materials is very attractive in both organic …
functional diversity from readily available starting materials is very attractive in both organic …
Recent Advances in Nucleophilic Lewis Base‐Catalyzed Cycloadditions for Synthesis of Spirooxindoles
QF Li, J Ma, J Meng, EQ Li - Advanced Synthesis & Catalysis, 2023 - Wiley Online Library
Spirooxindoles are privileged scaffolds in diverse bioactive natural products and
pharmaceuticals, significant achievements for the construction of these molecules have thus …
pharmaceuticals, significant achievements for the construction of these molecules have thus …
Convenient Synthetic Protocols for Diverse Functionalized Dihydrobenzofuran-Fused Spiro-indanedione-oxindole Scaffolds
J Sun, X Liu, Q Sun, Y Han, CG Yan - The Journal of Organic …, 2023 - ACS Publications
Diverse functionalized dihydrobenzofuran spiro-indanedione-oxindole scaffolds were
conveniently synthesized by base-promoted cyclization reaction of Morita–Baylis–Hillman …
conveniently synthesized by base-promoted cyclization reaction of Morita–Baylis–Hillman …
An access to highly functionalized dihydrobenzofuran spirooxindole scaffolds
D Wang, J Sun, Y Han, Q Sun, CG Yan - Organic Letters, 2022 - ACS Publications
We have developed an efficient protocol for the construction of polycyclic dihydrobenzofuran
spirooxindole scaffolds via base promoted cascade annulation of Morita–Baylis–Hillman …
spirooxindole scaffolds via base promoted cascade annulation of Morita–Baylis–Hillman …
Unmasking the reverse reactivity of cyclic N-sulfonyl ketimines: multifaceted applications in organic synthesis
The chemistry related to the exploration of cyclic N-sulfonyl ketimines and their derivatives
has attracted significant attention in the last few decades because of their intriguing …
has attracted significant attention in the last few decades because of their intriguing …
Efficient construction of diverse spiro [indoline-3, 4′-pyrrolo [3, 4-b] pyridines] via [3+ 3] cycloaddition of MBH carbonates of isatins with β-enamino maleimides
LN Pan, J Sun, XY Liu, CG Yan - Organic & Biomolecular Chemistry, 2022 - pubs.rsc.org
An efficient method to construct unique spiro [indoline-3, 4′-pyrrolo [3, 4-b] pyridines] was
successfully developed via a DABCO promoted formal [3+ 3] cycloaddition reaction of MBH …
successfully developed via a DABCO promoted formal [3+ 3] cycloaddition reaction of MBH …
Organocatalytic asymmetric synthesis of multifunctionalized α-carboline-spirooxindole hybrids that suppressed proliferation in colorectal cancer cells
XH He, XJ Fu, G Zhan, N Zhang, X Li, HP Zhu… - Organic Chemistry …, 2022 - pubs.rsc.org
Organocatalytic asymmetric [3+ 3] annulations of isatin-derived MBH carbonates and indolin-
2-imines were efficiently achieved. This appears to be the first enantioselective approach for …
2-imines were efficiently achieved. This appears to be the first enantioselective approach for …
Recent trends in catalytic sp 3 C–H functionalization of heterocycles
Heterocycles are a ubiquitous substructure in organic small molecules designed for use in
materials and medicines. Recent work in catalysis has focused on enabling access to new …
materials and medicines. Recent work in catalysis has focused on enabling access to new …
[HTML][HTML] Application of biobased solvents in asymmetric catalysis
The necessity of more sustainable conditions that follow the twelve principles of Green
Chemistry have pushed researchers to the development of novel reagents, catalysts and …
Chemistry have pushed researchers to the development of novel reagents, catalysts and …
Importance of Baylis-Hillman adducts in modern drug discovery
Abstract The Baylis-Hillman (BH) reaction plays a fascinating role in the field of synthetic and
medicinal chemistry. BH adducts and their derivatives have been used as crucial synthons …
medicinal chemistry. BH adducts and their derivatives have been used as crucial synthons …