Does diet play a role in reducing nociception related to inflammation and chronic pain?

G Bjørklund, J Aaseth, MD Doşa, L Pivina, M Dadar… - Nutrition, 2019 - Elsevier
Dietary habits are fundamental issues to assess when modulating health and well-being;
however, different nutritional panels may help individuals prevent acute and chronic pain …

In vitro and in vivo effects of flavonoids on peripheral neuropathic pain

P Basu, A Basu - Molecules, 2020 - mdpi.com
Neuropathic pain is a common symptom and is associated with an impaired quality of life. It
is caused by the lesion or disease of the somatosensory system. Neuropathic pain …

Flavonoids: A treasure house of prospective pharmacological potentials

H Hasnat, SA Shompa, MM Islam, S Alam, FT Richi… - Heliyon, 2024 - cell.com
Flavonoids are organic compounds characterized by a range of phenolic structures, which
are abundantly present in various natural sources such as fruits, vegetables, cereals, bark …

Exploring the promise of flavonoids to combat neuropathic pain: from molecular mechanisms to therapeutic implications

MS Uddin, AA Mamun, MA Rahman, MT Kabir… - Frontiers in …, 2020 - frontiersin.org
Neuropathic pain (NP) is the result of irregular processing in the central or peripheral
nervous system, which is generally caused by neuronal injury. The management of NP …

[HTML][HTML] Mitigation of sciatica injury-induced neuropathic pain through active metabolites derived from medicinal plants

A Nasir, OK Afridi, S Ullah, H Khan, Q Bai - Pharmacological Research, 2024 - Elsevier
Sciatica characterized by irritation, inflammation, and compression of the lower back nerve,
is considered one of the most common back ailments globally. Currently, the therapeutic …

Hesperetin and it nanocrystals ameliorate social behavior deficits and oxido-inflammatory stress in rat model of autism

R Khalaj, AH Moghaddam, M Zare - International Journal of Developmental …, 2018 - Elsevier
Prenatal exposure to valproic acid (VPA) induces behavioral disorders and enhancement of
oxido-inflammatory stress in Autism Spectrum Disorders (ASDs). The aim of this study was to …

Fabrication of hesperetin/hydroxypropyl-β-cyclodextrin complex nanoparticles for enhancement of bioactivity using supercritical antisolvent technology

C Wang, T Yan, T Yan, Z Wang - Journal of Molecular Structure, 2023 - Elsevier
Hesperetin (HST) is a bioflavonoid from citrus fruits and its clinical application is still
markedly limited by its poor water solubility (1.27 µg/mL). Herein, a complex nanoparticle …

Cinnamaldehyde and hesperetin attenuate TNBS‐induced ulcerative colitis in rats through modulation of the JAk2/STAT3/SOCS3 pathway

MG Elhennawy, EA Abdelaleem… - … of biochemical and …, 2021 - Wiley Online Library
Ulcerative colitis is an autoimmune inflammatory disorder with a negative impact on the life
quality of patients. Cinnamaldehyde and hesperetin were chosen due to their antioxidants …

[HTML][HTML] Physical properties and biological activities of hesperetin and naringenin in complex with methylated β-cyclodextrin

W Sangpheak, J Kicuntod, R Schuster… - Beilstein journal of …, 2015 - beilstein-journals.org
The aim of this work is to improve physical properties and biological activities of the two
flavanones hesperetin and naringenin by complexation with β-cyclodextrin (β-CD) and its …

Magnetic molecularly imprinted polymer for the selective extraction of hesperetin from the dried pericarp of Citrus reticulata Blanco

DD Wang, D Gao, WJ Xu, F Li, MN Yin, QF Fu, ZN **a - Talanta, 2018 - Elsevier
In present study, novel magnetic molecularly imprinted polymers for hesperetin were
successfully prepared by surface molecular imprinting method using functionalized Fe 3 O 4 …