A comprehensive review on tyrosinase inhibitors

S Zolghadri, A Bahrami, MT Hassan Khan… - Journal of enzyme …, 2019 - Taylor & Francis
Tyrosinase is a multi-copper enzyme which is widely distributed in different organisms and
plays an important role in the melanogenesis and enzymatic browning. Therefore, its …

Chalcone: a privileged structure in medicinal chemistry

C Zhuang, W Zhang, C Sheng, W Zhang, C **ng… - Chemical …, 2017 - ACS Publications
Privileged structures have been widely used as an effective template in medicinal chemistry
for drug discovery. Chalcone is a common simple scaffold found in many naturally occurring …

Skin whitening agents: Medicinal chemistry perspective of tyrosinase inhibitors

T Pillaiyar, M Manickam… - Journal of enzyme …, 2017 - Taylor & Francis
Melanogenesis is a process to synthesize melanin, which is a primary responsible for the
pigmentation of human skin, eye and hair. Although numerous enzymatic catalyzed and …

Recent advances in microalgal bioactives for food, feed, and healthcare products: commercial potential, market space, and sustainability

N MU, JG Mehar, SN Mudliar… - … reviews in food science …, 2019 - Wiley Online Library
To combat food scarcity as well as to ensure nutritional food supply for sustainable living of
increasing population, microalgae are considered as innovative sources for adequate …

Inhibitory kinetics and mechanism of kaempferol on α-glucosidase

X Peng, G Zhang, Y Liao, D Gong - Food Chemistry, 2016 - Elsevier
Abstract α-Glucosidase is a therapeutic target for diabetes mellitus, and α-glucosidase
inhibitors play a vital role in the treatments for the disease. As a kind of potentially safer α …

Natural skin‑whitening compounds for the treatment of melanogenesis

W Qian, W Liu, D Zhu, Y Cao… - Experimental and …, 2020 - spandidos-publications.com
Melanogenesis is the process for the production of melanin, which is the primary cause of
human skin pigmentation. Skin‑whitening agents are commercially available for those who …

[HTML][HTML] Bis-chalcones: A review of synthetic methodologies and anti-inflammatory effects

R Pereira, AMS Silva, D Ribeiro, VLM Silva… - European Journal of …, 2023 - Elsevier
Chalcones are bioactive molecules of natural and synthetic sources, whose
physicochemical properties, reactivity, and biological activities are well-known among the …

Chalcone hybrids as privileged scaffolds in antimalarial drug discovery: A key review

HL Qin, ZW Zhang, R Lekkala, H Alsulami… - European journal of …, 2020 - Elsevier
Malaria remains a serious worldwide health danger and massive economic trouble to
disease-endemic nations. Presently, 250 million of malarial cases are expected worldwide …

Validation of medicinal herbs for anti-tyrosinase potential

PK Mukherjee, R Biswas, A Sharma, S Banerjee… - Journal of herbal …, 2018 - Elsevier
Tyrosinase is a key regulatory multifunctional enzyme containing copper that is responsible
for the biosynthesis of melanin that determines the color of the skin. Accumulation of …

Recent discovery of tyrosinase inhibitors in traditional Chinese medicines and screening methods

J Li, C Li, X Peng, S Li, B Liu, C Chu - Journal of Ethnopharmacology, 2023 - Elsevier
Ethnopharmacological relevance Tyrosinase, the key rate-limiting enzyme for
melanogenesis, is one of the main targets for skin senescence and some pigmented skin …