Large-scale automated histology in the pursuit of connectomes

D Kleinfeld, A Bharioke, P Blinder, DD Bock… - Journal of …, 2011 - Soc Neuroscience
How does the brain compute? Answering this question necessitates neuronal connectomes,
annotated graphs of all synaptic connections within defined brain areas. Further …

Stacked sparse autoencoder (SSAE) for nuclei detection on breast cancer histopathology images

J Xu, L ** brain activity at scale with cluster computing
J Freeman, N Vladimirov, T Kawashima, Y Mu… - Nature …, 2014 - nature.com
Understanding brain function requires monitoring and interpreting the activity of large
networks of neurons during behavior. Advances in recording technology are greatly …

Cell type–specific three-dimensional structure of thalamocortical circuits in a column of rat vibrissal cortex

M Oberlaender, CPJ De Kock, RM Bruno… - Cerebral …, 2012 - academic.oup.com
Soma location, dendrite morphology, and synaptic innervation may represent key
determinants of functional responses of individual neurons, such as sensory-evoked spiking …

Breast cancer detection from biopsy images using nucleus guided transfer learning and belief based fusion

K George, S Faziludeen, P Sankaran - Computers in Biology and …, 2020 - Elsevier
Background and objective: Breast cancer is a frequently diagnosed cancer in women,
contributing to significant mortality rates. Death rates are relatively higher in develo** …

Number and laminar distribution of neurons in a thalamocortical projection column of rat vibrissal cortex

HS Meyer, VC Wimmer, M Oberlaender… - Cerebral …, 2010 - academic.oup.com
This is the second article in a series of three studies that investigate the anatomical
determinants of thalamocortical (TC) input to excitatory neurons in a cortical column of rat …

Extracting regions of interest from biological images with convolutional sparse block coding

M Pachitariu, AM Packer, N Pettit… - Advances in neural …, 2013 - proceedings.neurips.cc
Biological tissue is often composed of cells with similar morphologies replicated throughout
large volumes and many biological applications rely on the accurate identification of these …

Cellular organization of cortical barrel columns is whisker-specific

HS Meyer, R Egger, JM Guest… - Proceedings of the …, 2013 - National Acad Sciences
The cellular organization of the cortex is of fundamental importance for elucidating the
structural principles that underlie its functions. It has been suggested that reconstructing the …

Deep learning for automatic cell detection in wide-field microscopy zebrafish images

B Dong, L Shao, M Da Costa… - 2015 IEEE 12th …, 2015 - ieeexplore.ieee.org
The zebrafish has become a popular experimental model organism for biomedical research.
In this paper, a unique framework is proposed for automatically detecting Tyrosine …