The aggregation of proteins into amyloid fibrils and their deposition into plaques and
intracellular inclusions is the hallmark of amyloid disease. The accumulation and deposition …

The phenomenon of protein aggregation and amyloid formation has become the subject of
rapidly increasing research activities across a wide range of scientific disciplines. Such …

Eukaryotic cells contain assemblies of RNAs and proteins termed RNA granules. Many
proteins within these bodies contain KH or RRM RNA-binding domains as well as low …

The formation of amyloid fibrils is a general class of protein self-assembly behaviour, which
is associated with both functional biology and the development of a number of disorders …

Hierarchical self-assembly and crystallization with long-range ordered spatial arrangement
is ubiquitous in nature and plays an essential role in the regulation of structures and …

Abstract α-Synuclein (α-syn) is a 140-residue intrinsically disordered protein that is involved
in neuronal and synaptic vesicle plasticity, but its aggregation to form amyloid fibrils is the …

Amyloid–a fibrillar, cross β-sheet quaternary structure–was first discovered in the context of
human disease and tissue damage, and was thought to always be detrimental to the host …

Amyloid or amyloid-like fibrils represent a general class of nanomaterials that can be formed
from many different peptides and proteins. Although these structures have an important role …

In this tutorial review the process and applications of peptide self-assembly into nanotubes,
nanospheres, nanofibrils, nanotapes, and other ordered structures at the nano-scale are …

Background Microglia are the endogenous immune cells of the brain and act as sensors of
pathology to maintain brain homeostasis and eliminate potential threats. In Alzheimer's …