Microbial and animal rhodopsins: structures, functions, and molecular mechanisms

OP Ernst, DT Lodowski, M Elstner, P Hegemann… - Chemical …, 2014 - ACS Publications
Organisms of all domains of life use photoreceptor proteins to sense and respond to light.
The light-sensitivity of photoreceptor proteins arises from bound chromophores such as …

[HTML][HTML] Structure and function of the uncoupling protein from brown adipose tissue

M Klingenberg, SG Huang - Biochimica et Biophysica Acta (BBA) …, 1999 - Elsevier
Thermogenesis in brown adipose tissue (BAT) is attributed to uncoupling of respiration
which is caused by a speci¢ c component located in the inner mitochondrial membrane, the …

Structure of bacteriorhodopsin at 1.55 Å resolution

H Luecke, B Schobert, HT Richter, JP Cartailler… - Journal of molecular …, 1999 - Elsevier
The atomic structure of the light-driven ion pump bacteriorhodopsin and the surrounding
lipid matrix was determined by X-ray diffraction of crystals grown in cubic lipid phase. In the …

Functional waters in intraprotein proton transfer monitored by FTIR difference spectroscopy

F Garczarek, K Gerwert - Nature, 2006 - nature.com
Much progress has been made in our understanding of water molecule reactions on
surfaces, proton solvation in gas-phase water clusters, and proton transfer through liquids …

Proton transfer pathways in bacteriorhodopsin at 2.3 angstrom resolution

H Luecke, HT Richter, JK Lanyi - Science, 1998 - science.org
Photoisomerization of the retinal of bacteriorhodopsin initiates a cyclic reaction in which a
proton is translocated across the membrane. Studies of this protein promise a better …

Lipid patches in membrane protein oligomers: crystal structure of the bacteriorhodopsin-lipid complex

LO Essen, R Siegert, WD Lehmann… - Proceedings of the …, 1998 - pnas.org
Heterogenous nucleation on small molecule crystals causes a monoclinic crystal form of
bacteriorhodopsin (BR) in which trimers of this membrane protein pack differently than in …

Biomolecular electronics: protein-based associative processors and volumetric memories

RR Birge, NB Gillespie, EW Izaguirre… - The Journal of …, 1999 - ACS Publications
The promise of new architectures and more cost-effective miniaturization has prompted
interest in molecular and biomolecular electronics. Bioelectronics offers valuable near-term …

[HTML][HTML] Proton transfers in the bacteriorhodopsin photocycle

JK Lanyi - Biochimica et Biophysica Acta (BBA)-Bioenergetics, 2006 - Elsevier
The steps in the mechanism of proton transport in bacteriorhodopsin include examples for
most kinds of proton transfer reactions that might occur in a transmembrane pump: proton …

Structural alterations for proton translocation in the M state of wild-type bacteriorhodopsin

HJ Sass, G Büldt, R Gessenich, D Hehn, D Neff… - Nature, 2000 - nature.com
The transport of protons across membranes is an important process in cellular
bioenergetics. The light-driven proton pump bacteriorhodopsin is the best-characterized …

The structure and mechanism of the family of retinal proteins from halophilic archaea

D Oesterhelt - Current opinion in structural biology, 1998 - Elsevier
Retinal proteins from halophilic archaea provide a unique opportunity to analyze vectorial
ion translocation. Studies on its structure, conformational changes, proton conduction and …