Axons are generally considered as reliable transmission cables in which stable propagation
occurs once an action potential is generated. Axon dysfunction occupies a central position in …

The cerebellum is a central brain structure deeply integrated into major loops with the
cerebral cortex, brainstem, and spinal cord. The cerebellum shows a complex regional …

Most synaptic inputs are made onto the dendritic tree. Recent work has shown that dendrites
play an active role in transforming synaptic input into neuronal output and in defining the …

Neurons are generally considered to communicate information by increasing or decreasing
their firing rate. However, in principle, they could in addition convey messages by using …

Cerebellar dysfunction relates to various psychiatric disorders, including autism spectrum
and depressive disorders. However, the physiological aspect is less advanced. Here, we …

Understanding the transmission of sensory information at individual synaptic connections
requires knowledge of the properties of presynaptic terminals and their patterns of firing …

Cerebellar Purkinje cells integrate multimodal afferent inputs and, as the only projection
neurones of the cerebellar cortex, are key to the coordination of a variety of motor‐and …

Most spiking neurons are divided into functional compartments: a dendritic input region, a
soma, a site of action potential initiation, an axon trunk and its collaterals for propagation of …

Nicotinic acetylcholine receptors (nAChRs) are widely expressed throughout the central
nervous system and participate in a variety of physiological functions. Recent advances …

The output signal of Purkinje cells is conveyed by the modulated discharge of simple spikes
(SSs) often ascribed to mossy fiber–granule cell–parallel fiber inputs to Purkinje cell …