" The objectives of comparative physiology are:(1) to describe the diverse ways which
different kinds of animals meet their functional requirements;(2) to elucidate evolutionary …

Biochemical systems theory (BST) is the foundation for a set of analytical andmodeling tools
that facilitate the analysis of dynamic biological systems. This paper depicts major …

Dominance refers to the effect of a heterozygous genotype relative to that of the two
homozygous genotypes. The degree of dominance of mutations for fitness can have a …

Phosphoglucose isomerase genotypes in the butterfly Colias differ dramatically in
biochemical properties. These differences were evaluated earlier, using metabolic network …

The dominance of deleterious mutations has important consequences for phenomena such
as inbreeding depression, the evolution of diploidy, and levels of natural genetic variation …

In an attempt to understand whether it should be expected that some genes tend to be used
disproportionately often by natural selection, we investigated two related phenomena: the …

▪ Abstract Knowledge of both prokaryotic and eukaryotic organisms is essential to the study
of molecular evolution. Their common ancestry mandates that their molecular functions …

Arguments about the evolutionary modification of genetic dominance have a long history in
genetics, dating back more than 100 years. Mathematical investigations have shown that …

Although differences among species in enzyme maximal activity or concentration are often
interpreted as adaptive and important for regulating metabolism, these differences may …

The induction of effector genes that encode enzymes is often controlled by the protein
product of a regulator gene that is directly involved in the control of its own expression. This …