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Lipid metabolism and Alzheimer's disease: clinical evidence, mechanistic link and therapeutic promise
F Yin - The FEBS journal, 2023 - Wiley Online Library
Alzheimer's disease (AD) is an age‐associated neurodegenerative disorder with
multifactorial etiology, intersecting genetic and environmental risk factors, and a lack of …
multifactorial etiology, intersecting genetic and environmental risk factors, and a lack of …
Inflammation: the link between comorbidities, genetics, and Alzheimer's disease
Alzheimer's disease (AD) is a neurodegenerative disorder, most cases of which lack a clear
causative event. This has made the disease difficult to characterize and, thus, diagnose …
causative event. This has made the disease difficult to characterize and, thus, diagnose …
Bioactive lipids, inflammation and chronic diseases
A Leuti, D Fazio, M Fava, A Piccoli, S Oddi… - Advanced Drug Delivery …, 2020 - Elsevier
Endogenous bioactive lipids are part of a complex network that modulates a plethora of
cellular and molecular processes involved in health and disease, of which inflammation …
cellular and molecular processes involved in health and disease, of which inflammation …
Anti-inflammatory effects of omega-3 fatty acids in the brain: physiological mechanisms and relevance to pharmacology
Classically, polyunsaturated fatty acids (PUFA) were largely thought to be relatively inert
structural components of brain, largely important for the formation of cellular membranes …
structural components of brain, largely important for the formation of cellular membranes …
Physical exercise induces hippocampal neurogenesis and prevents cognitive decline
CL Ma, XT Ma, JJ Wang, H Liu, YF Chen… - Behavioural brain …, 2017 - Elsevier
Accumulating evidence from animal and human research indicate that adult hippocampal
neurogenesis plays a key role in cognition. Meanwhile, cognitive decline is well known to …
neurogenesis plays a key role in cognition. Meanwhile, cognitive decline is well known to …
Dementia and the risk of periodontitis: a population-based cohort study
KS Ma, H Hasturk, I Carreras… - Journal of dental …, 2022 - journals.sagepub.com
Dementia and Alzheimer's disease (AD) are proposed to be comorbid with periodontitis
(PD). It is unclear whether PD is associated with dementia and AD independent of …
(PD). It is unclear whether PD is associated with dementia and AD independent of …
Fatty acid metabolism in the progression and resolution of CNS disorders
Recent advances in lipidomics and metabolomics have unveiled the complexity of fatty acid
metabolism and the fatty acid lipidome in health and disease. A growing body of evidence …
metabolism and the fatty acid lipidome in health and disease. A growing body of evidence …
Lipoxins and aspirin-triggered lipoxins in resolution of inflammation
The resolution of the inflammatory response is highly regulated by the timely biosynthesis of
a number of endogenous lipid mediators. Among these, lipoxins (LX) and their 15-epimers …
a number of endogenous lipid mediators. Among these, lipoxins (LX) and their 15-epimers …
Neuroinflammation and neurohormesis in the pathogenesis of Alzheimer's disease and Alzheimer-linked pathologies: modulation by nutritional mushrooms
A Trovato Salinaro, M Pennisi, R Di Paola, M Scuto… - Immunity & …, 2018 - Springer
Human life develops and expands not only in time and space, but also in the retrograde
permanent recollection and interweaving of memories. Therefore, individual human identity …
permanent recollection and interweaving of memories. Therefore, individual human identity …
Expert consensus report on lipid mediators: role in resolution of inflammation and muscle preservation
This meeting report presents a consensus on the biological aspects of lipid emulsions in
parenteral nutrition, emphasizing the unanimous support for the integration of lipid …
parenteral nutrition, emphasizing the unanimous support for the integration of lipid …