Turnitin
降AI改写
早检测系统
早降重系统
Turnitin-UK版
万方检测-期刊版
维普编辑部版
Grammarly检测
Paperpass检测
checkpass检测
PaperYY检测
Efficacy of dextromethorphan for the treatment of depression: a systematic review of preclinical and clinical trials
Introduction The large percentage of adults with major depressive disorder (MDD)
insufficiently responding and/or tolerating conventional monoamine-based antidepressants …
insufficiently responding and/or tolerating conventional monoamine-based antidepressants …
Opioid receptor system contributes to the acute and sustained antidepressant-like effects, but not the hyperactivity motor effects of ketamine in mice
F Zhang, TM Hillhouse, PM Anderson… - Pharmacology …, 2021 - Elsevier
Abstract In 2000, a subanesthetic dose (0.5 mg/kg iv) of the dissociative anesthetic ketamine
was reported to have both rapid and robust antidepressant effects in patients diagnosed with …
was reported to have both rapid and robust antidepressant effects in patients diagnosed with …
Repurposing of dextromethorphan as an adjunct therapy in patients with major depressive disorder: a randomised, group sequential adaptive design, controlled …
Background Therapeutic latency, lack of efficacy and adverse drug reactions are the major
concerns in current antidepressant therapies. To overcome these treatment hurdles, add-on …
concerns in current antidepressant therapies. To overcome these treatment hurdles, add-on …
Delta opioid receptor-mediated antidepressant-like effects of diprenorphine in mice
Major depressive disorder is a highly common disorder, with a lifetime prevalence in the
United States of approximately 21%. Traditional antidepressant treatments are limited by a …
United States of approximately 21%. Traditional antidepressant treatments are limited by a …
Nicotine-free vapor inhalation produces behavioral disruptions and anxiety-like behaviors in mice: Effects of puff duration, session length, sex, and flavor
PI Garrett, SC Honeycutt, C Marston, N Allen… - Pharmacology …, 2021 - Elsevier
Abstract Electronic-cigarette's (ECIGs) popularity has grown over the last decade and
changed the way individuals administer nicotine. Preclinical research is imperative for …
changed the way individuals administer nicotine. Preclinical research is imperative for …
Early augmentation therapy with dextromethorphan in mild to moderate major depressive disorder: A group sequential, response adaptive randomized controlled trial
Aim Therapeutic latency, lack of response, and adverse drug reactions are major challenges
in current treatment approaches for major depressive disorder (MDD). Following the success …
in current treatment approaches for major depressive disorder (MDD). Following the success …
Targeting mediodorsal thalamic CB1 receptors to inhibit dextromethorphan-induced anxiety/exploratory-related behaviors in rats: The post-weaning effect of exercise …
Dextromethorphan (DXM) is an effective over-the-counter antitussive with an alarming
increase as an abused drug for recreational purposes. Although reports of the association …
increase as an abused drug for recreational purposes. Although reports of the association …
Assessment of antidepressant-like effects of dextromethorphan on differential reinforcement of low-rate 72-s performance in rats
CJ Lynch, AJ Prus - Behavioural Pharmacology, 2021 - journals.lww.com
The effectiveness of ketamine for treatment-resistant depression along with several other
clinical advantages, such as rapid onset and reduced adverse effects associated with …
clinical advantages, such as rapid onset and reduced adverse effects associated with …
Ketamine and Other Glutamate Receptor Antagonists As Fast-Actin
MH Chen, TP Su, SJ Tsai - Translational Research Methods for Major …, 2022 - Springer
The glutamate hypothesis of depression was prominently emerging in this decade. Evidence
has shown that low-dose ketamine infusion or intranasal S-ketamine spray exhibited a …
has shown that low-dose ketamine infusion or intranasal S-ketamine spray exhibited a …