Radiopharmaceuticals: navigating the frontier of precision medicine and therapeutic innovation

S Dhoundiyal, S Srivastava, S Kumar, G Singh… - European Journal of …, 2024 - Springer
This review article explores the dynamic field of radiopharmaceuticals, where innovative
developments arise from combining radioisotopes and pharmaceuticals, opening up …

Theranostics and artificial intelligence: new frontiers in personalized medicine

GB Bilgin, C Bilgin, BJ Burkett, JJ Orme… - …, 2024 - pmc.ncbi.nlm.nih.gov
The field of theranostics is rapidly advancing, driven by the goals of enhancing patient care.
Recent breakthroughs in artificial intelligence (AI) and its innovative theranostic applications …

Toward single-time-point image-based dosimetry of 177Lu-PSMA-617 therapy

J Brosch-Lenz, A Delker, F Völter… - Journal of Nuclear …, 2023 - jnm.snmjournals.org
Radiopharmaceutical therapies (RPTs) with 177Lu-prostate-specific membrane antigen
(PSMA) ligands have demonstrated promising results for the treatment of metastatic …

Artificial intelligence in nuclear medicine: opportunities, challenges, and responsibilities toward a trustworthy ecosystem

B Saboury, T Bradshaw, R Boellaard… - Journal of Nuclear …, 2023 - jnm.snmjournals.org
Trustworthiness is a core tenet of medicine. The patient–physician relationship is evolving
from a dyad to a broader ecosystem of health care. With the emergence of artificial …

Radiomics and artificial intelligence in radiotheranostics: a review of applications for radioligands targeting somatostatin receptors and prostate-specific membrane …

E Yazdani, P Geramifar, N Karamzade-Ziarati… - Diagnostics, 2024 - mdpi.com
Radiotheranostics refers to the pairing of radioactive imaging biomarkers with radioactive
therapeutic compounds that deliver ionizing radiation. Given the introduction of very …

Automated segmentation of lesions and organs at risk on [68Ga]Ga-PSMA-11 PET/CT images using self-supervised learning with Swin UNETR

E Yazdani, N Karamzadeh-Ziarati, SS Cheshmi… - Cancer Imaging, 2024 - Springer
Background Prostate-specific membrane antigen (PSMA) PET/CT imaging is widely used for
quantitative image analysis, especially in radioligand therapy (RLT) for metastatic castration …

Deep transformer-based personalized dosimetry from SPECT/CT images: a hybrid approach for [177Lu]Lu-DOTATATE radiopharmaceutical therapy

Z Mansouri, Y Salimi, A Akhavanallaf, I Shiri… - European journal of …, 2024 - Springer
Purpose Accurate dosimetry is critical for ensuring the safety and efficacy of
radiopharmaceutical therapies. In current clinical dosimetry practice, MIRD formalisms are …

[HTML][HTML] Personalized dosimetry in targeted radiation therapy: a look to methods, tools and critical aspects

R Danieli, A Milano, S Gallo, I Veronese… - Journal of Personalized …, 2022 - mdpi.com
Targeted radiation therapy (TRT) is a strategy increasingly adopted for the treatment of
different types of cancer. The urge for optimization, as stated by the European Council …

[HTML][HTML] Future perspectives of artificial intelligence in bone marrow dosimetry and individualized radioligand therapy

A Moraitis, A Küper, J Tran-Gia, U Eberlein… - Seminars in nuclear …, 2024 - Elsevier
Radioligand therapy is an emerging and effective treatment option for various types of
malignancies, but may be intricately linked to hematological side effects such as anemia …

AI-based detection, classification and prediction/prognosis in medical imaging: towards radiophenomics

F Yousefirizi, P Decazes, A Amyar, S Ruan… - PET clinics, 2022 - pet.theclinics.com
The task of clinical interpretation of medical images starts with the scanning of the presented
image to detect the suspicious finding (“observation” in RadLex terminology (RID5) 1 which …