Ischemic heart disease pathophysiology paradigms overview: from plaque activation to microvascular dysfunction

P Severino, A D'Amato, M Pucci, F Infusino… - International journal of …, 2020 - mdpi.com
Ischemic heart disease still represents a large burden on individuals and health care
resources worldwide. By conventions, it is equated with atherosclerotic plaque due to flow …

Characteristics, prevention, and management of cardiovascular disease in people living with HIV: a scientific statement from the American Heart Association

MJ Feinstein, PY Hsue, LA Benjamin, GS Bloomfield… - Circulation, 2019 - ahajournals.org
As early and effective antiretroviral therapy has become more widespread, HIV has
transitioned from a progressive, fatal disease to a chronic, manageable disease marked by …

2018 AHA/ACC/AACVPR/AAPA/ABC/ACPM/ADA/AGS/APhA/ASPC/NLA/PCNA guideline on the management of blood cholesterol: executive summary: a report of the …

SM Grundy, NJ Stone, AL Bailey, C Beam… - Journal of the American …, 2019 - jacc.org
2018 AHA/ACC/AACVPR/AAPA/ABC/ACPM/ADA/AGS/APhA/ASPC/NLA/PCNA Guideline on
the Management of Blood Cholesterol: Executive Summary: A Report of the American …

2018 AHA/ACC/AACVPR/AAPA/ABC/ACPM/ADA/AGS/APhA/ASPC/NLA/PCNA guideline on the management of blood cholesterol: a report of the American College of …

SM Grundy, NJ Stone, AL Bailey, C Beam… - Journal of the American …, 2019 - jacc.org
The recommendations listed in the present guideline are, whenever possible, evidence
based. An initial extensive evidence review, which included literature derived from research …

Cardiovascular diseases in sub-Saharan Africa compared to high-income countries: an epidemiological perspective

MF Yuyun, K Sliwa, AP Kengne, AO Mocumbi… - Global …, 2020 - pmc.ncbi.nlm.nih.gov
Non-communicable diseases (NCDs) are the second common cause of death in sub-
Saharan Africa (SSA) accounting for about 35% of all deaths, after a composite of …

Epidemiology of cardiovascular disease in young individuals

C Andersson, RS Vasan - Nature Reviews Cardiology, 2018 - nature.com
In the past 2 decades, a high prevalence of risk factors for cardiovascular disease, such as
obesity, physical inactivity, and poor diet, has been observed among young individuals …

Initiation of antiretroviral therapy in early asymptomatic HIV infection

Insight Start Study Group - New England Journal of Medicine, 2015 - Mass Medical Soc
Background Data from randomized trials are lacking on the benefits and risks of initiating
antiretroviral therapy in patients with asymptomatic human immunodeficiency virus (HIV) …

HIV infection and the risk of acute myocardial infarction

MS Freiberg, CCH Chang, LH Kuller… - JAMA internal …, 2013 - jamanetwork.com
Importance Whether people infected with human immunodeficiency virus (HIV) are at an
increased risk of acute myocardial infarction (AMI) compared with uninfected people is not …

[HTML][HTML] Tenofovir alafenamide: a novel prodrug of tenofovir for the treatment of human immunodeficiency virus

AS Ray, MW Fordyce, MJM Hitchcock - Antiviral research, 2016 - Elsevier
Despite substantial progress in the development of antiretroviral regimens that durably
suppress Human Immunodeficiency Virus (HIV) infection, new agents that maintain high …

Autoimmunity, checkpoint inhibitor therapy and immune-related adverse events: A review

S Khan, DE Gerber - Seminars in cancer biology, 2020 - Elsevier
Immune checkpoint inhibitors have emerged as a remarkable treatment option for diverse
cancer types. However, a significant number of patients on checkpoint inhibitors develop …