Role of the intestinal microbiome and its therapeutic intervention in cardiovascular disorder

A Luqman, A Hassan, M Ullah, S Naseem… - Frontiers in …, 2024 - frontiersin.org
The gut microbiome is a heterogeneous population of microbes comprising viruses,
bacteria, fungi, and protozoa. Such a microbiome is essential for sustaining host equilibrium …

[HTML][HTML] Role of gut microbial metabolites in the pathogenesis of primary liver cancers

M Pallozzi, V De Gaetano, N Di Tommaso, L Cerrito… - Nutrients, 2024 - mdpi.com
Hepatobiliary malignancies, which include hepatocellular carcinoma (HCC) and
cholangiocarcinoma (CCA), are the sixth most common cancers and the third leading cause …

Urine metabolites and bioactive compounds from functional food: applications of liquid chromatography mass spectrometry

ES Ong - Critical Reviews in Analytical Chemistry, 2024 - Taylor & Francis
Bioactive compounds in functional foods, medicinal plants and others are considered
attractive value-added molecules based on their wide range of bioactivity. It is clear that an …

Recent advances in the combination of organic solvent-free extraction, chemical standardization, antioxidant assay, and cell culture metabolomics for functional food …

CH Leo, ES Ong - Critical Reviews in Food Science and Nutrition, 2024 - Taylor & Francis
Functional foods and their by-products contain a wide range of bioactive components with
an array of health benefits and were proposed to improve public health, well-being, and …

Regulation of SARS-CoV-2 infection by diet-modulated gut microbiota

V Tieu, S Tibi, J Ling - Frontiers in Cellular and Infection Microbiology, 2023 - frontiersin.org
Coronavirus disease 2019 (COVID-19) caused by SARS-CoV-2 infection has claimed
millions of lives since late 2019, yet there are still many unexplored areas in its …

Gut microbiome‐derived metabolites in Alzheimer's disease: Regulation of immunity and potential for therapeutics

S Chandra, RJ Vassar - Immunological Reviews, 2024 - Wiley Online Library
Alzheimer's disease (AD) is the most common neurodegenerative disorder and cause of
dementia. Despite the prevalence of AD, there is a lack of effective disease modifying …

[HTML][HTML] Trimethylamine-N-oxide and cerebral stroke risk: A review

P Dolkar, T Deyang, N Anand, AG Rathipriya… - Neurobiology of …, 2024 - Elsevier
Abstract Trimethylamine-N-oxide (TMAO) is a gut microbiota-derived metabolite produced
by the action of gut microbiota and the hepatic enzyme Flavin Mono‑oxygenase 3 (FMO3) …

1H NMR Serum Metabolomic Change of Trimethylamine N-oxide (TMAO) Is Associated with Alcoholic Liver Disease Progression

J Oh, J Kim, S Lee, G Park, KAG Baritugo, KJ Han… - Metabolites, 2024 - mdpi.com
Without early detection and treatment, chronic and excessive alcohol consumption can lead
to the development of alcoholic liver disease (ALD). With this in mind, we exploit the recent …

Therapeutic potential of relaxin or relaxin mimetics in managing cardiovascular complications of diabetes

AG Devasia, M Shanmugham, A Ramasamy… - Biochemical …, 2024 - Elsevier
Diabetes mellitus is a metabolic disease with an escalating global prevalence. Despite the
abundance and relative efficacies of current therapeutic approaches, they primarily focus on …

A review of gut microbial metabolites and therapeutic approaches in hypertension

SO Olalekan, OO Bakare, AS Faponle… - Bulletin of the National …, 2024 - Springer
Background Hypertension is a prevalent and complex disease that is increasingly
recognized to be influenced by the gut microbiome and its metabolites. Understanding the …