It is an urgent need that defect repair can develop from simple device fixation to living tissue
reconstruction, from short life function replacement to permanent regeneration repair. At …

Bones play an important role in maintaining exercise and protecting organs. Bone defect, as
a common orthopedic disease in clinics, can cause tremendous damage with long treatment …

Engineering a proper immune response following biomaterial implantation is essential to
bone tissue regeneration. Herein, a biomimetically hierarchical scaffold composed of …

Bone tissue engineering (BTE) is a rapidly growing field aiming to create a biofunctional
tissue that can integrate and degrade in vivo to treat diseased or damaged tissue. It has …

Trauma-and disease-related skeletal defects and illnesses are plaguing millions of people
especially in an ageing globe. Recently, the convergence of additive manufacturing (AM) …

The favorable microstructure and bioactivity of tissue-engineered bone scaffolds are closely
associated with the regenerative efficacy of bone defects. For the treatment of large bone …

Successful materials design for bone-tissue engineering requires an understanding of the
composition and structure of native bone tissue, as well as appropriate selection of …

Due to a prolonged life expectancy, the number of orthopedic-related fractures and
pathologies is increasing, leading to a tremendous demand for efficient orthopedic …

The treatment of bone defects remains a substantial clinical challenge due to the lack of
spatiotemporal management of the immune microenvironment, revascularization, and …

Blood vessels are essential for nutrient and oxygen delivery and waste removal. Scaffold-
repairing materials with functional vascular networks are widely used in bone tissue …