Monocytes and macrophages: developmental pathways and tissue homeostasis

F Ginhoux, S Jung - Nature Reviews Immunology, 2014 - nature.com
Monocytes and macrophages have crucial and distinct roles in tissue homeostasis and
immunity, but they also contribute to a broad spectrum of pathologies and are thus attractive …

Monocyte recruitment during infection and inflammation

C Shi, EG Pamer - Nature reviews immunology, 2011 - nature.com
Monocytes originate from progenitors in the bone marrow and traffic via the bloodstream to
peripheral tissues. During both homeostasis and inflammation, circulating monocytes leave …

Guidelines for the use of flow cytometry and cell sorting in immunological studies

A Cossarizza, HD Chang, A Radbruch… - European journal of …, 2019 - Wiley Online Library
These guidelines are a consensus work of a considerable number of members of the
immunology and flow cytometry community. They provide the theory and key practical …

The dendritic cell lineage: ontogeny and function of dendritic cells and their subsets in the steady state and the inflamed setting

M Merad, P Sathe, J Helft, J Miller… - Annual review of …, 2013 - annualreviews.org
Dendritic cells (DCs) form a remarkable cellular network that shapes adaptive immune
responses according to peripheral cues. After four decades of research, we now know that …

The dynamics of the skin's immune system

AV Nguyen, AM Soulika - International journal of molecular sciences, 2019 - mdpi.com
The skin is a complex organ that has devised numerous strategies, such as physical,
chemical, and microbiological barriers, to protect the host from external insults. In addition …

Dendritic cell regulation of T helper cells

X Yin, S Chen, SC Eisenbarth - Annual review of immunology, 2021 - annualreviews.org
As the professional antigen-presenting cells of the immune system, dendritic cells (DCs)
sense the microenvironment and shape the ensuing adaptive immune response. DCs can …

The immunological anatomy of the skin

K Kabashima, T Honda, F Ginhoux… - Nature Reviews …, 2019 - nature.com
The skin is the outermost organ of the body and is continuously exposed to external
pathogens. Upon inflammation, various immune cells pass through, reside in or are …

Dendritic cell migration in health and disease

T Worbs, SI Hammerschmidt, R Förster - Nature Reviews Immunology, 2017 - nature.com
Dendritic cells (DCs) are potent and versatile antigen-presenting cells, and their ability to
migrate is key for the initiation of protective pro-inflammatory as well as tolerogenic immune …

Inflammatory monocytes recruited after skeletal muscle injury switch into antiinflammatory macrophages to support myogenesis

L Arnold, A Henry, F Poron, Y Baba-Amer… - The Journal of …, 2007 - rupress.org
Macrophages (MPs) are important for skeletal muscle regeneration in vivo and may exert
beneficial effects on myogenic cell growth through mitogenic and antiapoptotic activities in …

Monitoring of blood vessels and tissues by a population of monocytes with patrolling behavior

C Auffray, D Fogg, M Garfa, G Elain, O Join-Lambert… - Science, 2007 - science.org
The cellular immune response to tissue damage and infection requires the recruitment of
blood leukocytes. This process is mediated through a classical multistep mechanism, which …