Mechanics of the mitral valve: a critical review, an in vivo parameter identification, and the effect of prestrain

MK Rausch, N Famaey, TOB Shultz, W Bothe… - … and modeling in …, 2013‏ - Springer
Alterations in mitral valve mechanics are classical indicators of valvular heart disease, such
as mitral valve prolapse, mitral regurgitation, and mitral stenosis. Computational modeling is …

On the effect of prestrain and residual stress in thin biological membranes

MK Rausch, E Kuhl - Journal of the Mechanics and Physics of Solids, 2013‏ - Elsevier
Understanding the difference between ex vivo and in vivo measurements is critical to
interpret the load carrying mechanisms of living biological systems. For the past four …

Computational mitral valve evaluation and potential clinical applications

KB Chandran, H Kim - Annals of biomedical engineering, 2015‏ - Springer
The mitral valve (MV) apparatus consists of the two asymmetric leaflets, the saddle-shaped
annulus, the chordae tendineae, and the papillary muscles. MV function over the cardiac …

On the In Vivo Deformation of the Mitral Valve Anterior Leaflet: Effects of Annular Geometry and Referential Configuration

R Amini, CE Eckert, K Koomalsingh… - Annals of biomedical …, 2012‏ - Springer
Alteration of the native mitral valve (MV) shape has been hypothesized to have a profound
effect on the local tissue stress distribution, and is potentially linked to limitations in repair …

[HTML][HTML] Clinical evaluation of functional mitral stenosis after mitral valve repair for degenerative disease: potential affect on surgical strategy

TG Mesana, BK Lam, V Chan, K Chen, M Ruel… - The Journal of Thoracic …, 2013‏ - Elsevier
Background Mitral annuloplasty with either a partial band or complete ring is an integral part
of mitral valve repair for degenerative disease. The affect of annuloplasty type on outcomes …

A fully implicit finite element method for bidomain models of cardiac electromechanics

H Dal, S Göktepe, M Kaliske, E Kuhl - Computer methods in applied …, 2013‏ - Elsevier
We propose a novel, monolithic, and unconditionally stable finite element algorithm for the
bidomain-based approach to cardiac electromechanics. We introduce the transmembrane …

A noninvasive method for the determination of in vivo mitral valve leaflet strains

BV Rego, AH Khalighi, A Drach, EK Lai… - … journal for numerical …, 2018‏ - Wiley Online Library
Assessment of mitral valve (MV) function is important in many diagnostic, prognostic, and
surgical planning applications for treatment of MV disease. Yet, to date, there are no …

Evidence of adaptive mitral leaflet growth

MK Rausch, FA Tibayan, DC Miller, E Kuhl - journal of the mechanical …, 2012‏ - Elsevier
Ischemic mitral regurgitation is mitral insufficiency caused by myocardial infarction. Recent
studies suggest that mitral leaflets have the potential to grow and reduce the degree of …

Mitral valve annuloplasty: a quantitative clinical and mechanical comparison of different annuloplasty devices

MK Rausch, W Bothe, JPE Kvitting, JC Swanson… - Annals of biomedical …, 2012‏ - Springer
Mitral valve annuloplasty is a common surgical technique used in the repair of a leaking
valve by implanting an annuloplasty device. To enhance repair durability, these devices are …

A computational pipeline for patient-specific prediction of the postoperative mitral valve functional state

H Liu, NT Simonian, AM Pouch… - Journal of …, 2023‏ - asmedigitalcollection.asme.org
While mitral valve (MV) repair remains the preferred clinical option for mitral regurgitation
(MR) treatment, long-term outcomes remain suboptimal and difficult to predict. Furthermore …