The genetic factors of the airway epithelium associated with the pathology of asthma

M Ranjbar, CE Whetstone, H Omer, L Power… - Genes, 2022 - mdpi.com
Asthma is a chronic disease of the airways characterized by inflammation, tightened
muscles, and thickened airway walls leading to symptoms such as shortness of breath, chest …

Associations between vitamin D status and biomarkers linked with inflammation in patients with asthma: a systematic review and meta-analysis of interventional and …

A El Abd, H Dasari, P Dodin, H Trottier… - Respiratory …, 2024 - Springer
Background Numerous studies indicate an association between vitamin D status and
inflammatory biomarkers in patients with asthma, but findings are inconsistent. This review …

Vitamin D3 decreases TNF-α-induced inflammation in lung epithelial cells through a reduction in mitochondrial fission and mitophagy

YC Chen, HC Sung, TY Chuang, TC Lai, TL Lee… - Cell biology and …, 2022 - Springer
Previous work has shown an association between vitamin D3 deficiency and an increased
risk for acquiring various inflammatory diseases. Vitamin D3 can reduce morbidity and …

VDR Gene Polymorphisms and Allergic Diseases: Evidence from a Meta-analysis

L Zhang, S Zhang, C He, X Wang - Immunological investigations, 2020 - Taylor & Francis
Associations between vitamin D receptor (VDR) gene polymorphisms and allergic diseases
were already reported by many publications. The aim of this meta-analysis was to clarify …

Vitamin D receptor gene polymorphism and susceptibility to asthma: meta-analysis based on 17 case-control studies

MH Makoui, D Imani, M Motallebnezhad… - Annals of Allergy …, 2020 - Elsevier
Background During the last decade, several studies have evaluated the potential
association between vitamin D receptor (VDR) gene polymorphism and susceptibility to …

Genetic polymorphisms in vitamin D pathway influence 25 (OH) D levels and are associated with atopy and asthma

AA Galvão, F de Araújo Sena… - Allergy, Asthma & …, 2020 - Springer
Background Vitamin D deficiency or insufficiency, has been associated with atopy and lack
of asthma control. Our objective was to investigate associations between variants in genes …

[HTML][HTML] Relation of T Cell Profile with Vitamin D Receptor and Vitamin D-Binding Protein Gene Polymorphisms in Atopy

D Bastyte, L Tamasauskiene, I Stakaitiene… - International Journal of …, 2024 - mdpi.com
Atopic diseases, including atopic dermatitis (AD) and allergic asthma (AA), are characterized
by complex immune responses involving various T cells subsets and their cytokine profiles …

Rhinovirus and asthma exacerbations

JL Kennedy, S Pham, L Borish - … and Allergy Clinics, 2019 - immunology.theclinics.com
Asthma is an increasing public health concern with more than 8% of children and adults now
having this condition. 1, 2 Asthma exacerbations, or loss of symptom control that includes …

The vitamin D receptor gene polymorphisms in asthmatic children: a case-control study

M Kilic, S Ecin, E Taskin, A Sen… - … allergy, immunology, and …, 2019 - liebertpub.com
Background: The association between vitamin D receptor (VDR) polymorphisms and the risk
of asthma remains unclear. This study aimed to investigate the effect of VDR gene …

Viral induced effects on a vulnerable epithelium; lessons learned from paediatric asthma and eosinophilic oesophagitis

RL Watkinson, K Looi, IA Laing, A Cianferoni… - Frontiers in …, 2021 - frontiersin.org
The epithelium is integral to the protection of many different biological systems and for the
maintenance of biochemical homeostasis. Emerging evidence suggests that particular …