Sulfonyl fluorides as targets and substrates in the development of new synthetic methods
The advent of sulfur (vi)-fluoride exchange (SuFEx) processes as transformations with click-
like reactivity has invigorated research into electrophilic species featuring a sulfur–fluorine …
like reactivity has invigorated research into electrophilic species featuring a sulfur–fluorine …
Emerging building blocks for medicinal chemistry: recent synthetic advances
Current medicinal chemistry relies heavily on the quality of building blocks, ie reagents used
to introduce chemical diversity into the target molecules. The last decade witnessed an …
to introduce chemical diversity into the target molecules. The last decade witnessed an …
Ethenesulfonyl fluoride (ESF) and its derivatives in SuFEx click chemistry and more
YP Meng, SM Wang, WY Fang, ZZ **e, J Leng… - …, 2020 - thieme-connect.com
The sulfur (VI) fluoride exchange reaction (SuFEx), developed by Sharpless and co-workers
in 2014, is a new category of click reaction that creates molecular connections with absolute …
in 2014, is a new category of click reaction that creates molecular connections with absolute …
Recent Advances of S–18F Radiochemistry for Positron Emission Tomography
X Deng, X Zhu - ACS omega, 2023 - ACS Publications
The click chemistry of sulfur (VI) fluoride exchange (SuFEx) has facilitated the widespread
application of sulfur–fluoride compounds such as sulfonyl fluorides, fluorosulfates, and …
application of sulfur–fluoride compounds such as sulfonyl fluorides, fluorosulfates, and …
State of the art procedures towards reactive [18F]fluoride in PET tracer synthesis
LYF Haveman, DJ Vugts, AD Windhorst - EJNMMI Radiopharmacy and …, 2023 - Springer
Background Positron emission tomography (PET) is a powerful, non-invasive preclinical and
clinical nuclear imaging technique used in disease diagnosis and therapy assessment …
clinical nuclear imaging technique used in disease diagnosis and therapy assessment …
Synthesis and 18F Labeling of Alkenyl Sulfonyl Fluorides via an Unconventional Elimination Pathway
W Zhang, X Deng, FX Zhang, JH Lin, JC **ao… - Organic …, 2022 - ACS Publications
A successful Cu-catalyzed addition of both Cl and SO2OCF2H groups into alkenes allows
us to discover the unusual reactivity of the SO2OCF2H group. As opposed to common …
us to discover the unusual reactivity of the SO2OCF2H group. As opposed to common …
Aliphatic 18F‐Radiofluorination: Recent Advances in the Labeling of Base‐Sensitive Substrates**
K Bratteby, V Shalgunov, MM Herth - ChemMedChem, 2021 - Wiley Online Library
Aliphatic fluorine‐18 radiolabeling is the most commonly used method to synthesize tracers
for PET‐imaging. With an increasing demand for 18F‐radiotracers for clinical applications …
for PET‐imaging. With an increasing demand for 18F‐radiotracers for clinical applications …
Microfluidic synthesis of radiotracers: recent developments and commercialization prospects
Positron emission tomography (PET) is a powerful diagnostic tool that holds incredible
potential for clinicians to track a wide variety of biological processes using specialized …
potential for clinicians to track a wide variety of biological processes using specialized …
Fluorine‐18 Radiolabelling and Photophysical Characteristics of Multimodal PET–Fluorescence Molecular Probes
Positron emission tomography (PET)–fluorescence imaging is an emerging field of
multimodality imaging seeking to attain synergy between the two techniques. The probes …
multimodality imaging seeking to attain synergy between the two techniques. The probes …
Synthesis of 18F-Labeled Aryl Fluorosulfates via Nucleophilic Radiofluorination
YD Kwon, MH Jeon, NK Park, JK Seo, J Son… - Organic …, 2020 - ACS Publications
Sulfuryl fluoride gas is a key reagent for SO2F transfer. However, conventional SO2F
transfer reactions have limited 18F-radiochemistry translation, due to the inaccessibility of …
transfer reactions have limited 18F-radiochemistry translation, due to the inaccessibility of …