Light-sheet fluorescence microscopy has transformed our ability to visualize and
quantitatively measure biological processes rapidly and over long time periods. In this …

The promise of single-objective light-sheet microscopy is to combine the convenience of
standard single-objective microscopes with the speed, coverage, resolution and gentleness …

In recent years, there has been a revived appreciation for the importance of spatial context
and morphological phenotypes for both understanding disease progression and guiding …

Light-sheet microscopy has emerged as the preferred means for high-throughput volumetric
imaging of cleared tissues. However, there is a need for a flexible system that can address …

Due to the size and opacity of vertebrate brains, it has until now been impossible to
simultaneously record neuronal activity at cellular resolution across the entire adult brain. As …

Planar optics based on patterned cholesteric liquid crystals (CLCs) has attracted increasing
attention owing to the self‐organized helical structure and the ability to create arbitrary …

Understanding the intricate interplay and inter-connectivity of biological processes across an
entire organism is important in various fields of biology, including cardiovascular research …

Danionella cerebrum (DC) is a promising vertebrate animal model for systems neuroscience
due to its small adult brain volume and inherent optical transparency, but the scope of their …

Oblique plane microscopy (OPM) directly captures object information in a plane tilted from
the focal plane of the objective lens without the need for slow z-stack acquisition. This …

Fundamental understanding of large-scale<? TeX 2pc 0pt?> dynamic connectivity within a
living organism requires volumetric imaging over a large field of view (FOV) at biologically …