Matrix metalloproteinase contribution in management of cancer proliferation, metastasis and drug targeting
Matrix metalloproteinases (MMPs) or matrixins, are members of a zinc-dependent
endopeptidase family. They cause remodeling of the extracellular matrix (ECM) leading to …
endopeptidase family. They cause remodeling of the extracellular matrix (ECM) leading to …
Regulation and function of matrix metalloproteinase-13 in cancer progression and metastasis
Simple Summary MMP-13 is an enzyme that can digest and disrupt the tissue structures
surrounding epithelial cells that line the surface of many internal organs, as well as the …
surrounding epithelial cells that line the surface of many internal organs, as well as the …
Matrix metalloproteinases in non-neoplastic disorders
A Tokito, M Jougasaki - International journal of molecular sciences, 2016 - mdpi.com
The matrix metalloproteinases (MMPs) are zinc-dependent endopeptidases belonging to the
metzincin superfamily. There are at least 23 members of MMPs ever reported in human, and …
metzincin superfamily. There are at least 23 members of MMPs ever reported in human, and …
Remodeling of the interstitial extracellular matrix in white matter multiple sclerosis lesions: Implications for remyelination (failure)
JM de Jong, P Wang, M Oomkens… - Journal of …, 2020 - Wiley Online Library
The extracellular matrix (ECM) provides protection, rigidity, and structure toward cells. It
consists, among others, of a wide variety of glycoproteins and proteoglycans, which act …
consists, among others, of a wide variety of glycoproteins and proteoglycans, which act …
Candidate prognostic markers in breast cancer: focus on extracellular proteases and their inhibitors
The extracellular matrix (ECM) is the complex network of proteins that surrounds cells in
multicellular organisms. Due to its diverse nature and composition, the ECM has a …
multicellular organisms. Due to its diverse nature and composition, the ECM has a …
The effect of ginger (Zingiber officinale) supplementation on clinical, biochemical, and anthropometric parameters in patients with multiple sclerosis: a double-blind …
Introduction: different lines of evidence have shown that ginger administration may be
beneficial for patients with multiple sclerosis (MS). Therefore, we aimed to investigate the …
beneficial for patients with multiple sclerosis (MS). Therefore, we aimed to investigate the …
[HTML][HTML] Matrix metalloproteinases and tissue inhibitors of metalloproteinases in murine β-coronavirus-induced neuroinflammation
Mouse hepatitis virus (MHV; m-β-CoV) serves as a useful model for studying the cellular
factors involved in neuroinflammation. To understand the role of matrix metalloproteinases …
factors involved in neuroinflammation. To understand the role of matrix metalloproteinases …
The versatile role of matrix metalloproteinase for the diverse results of fibrosis treatment
Fibrosis is a type of chronic organ failure, resulting in the excessive secretion of extracellular
matrix (ECM). ECM protects wound tissue from infection and additional injury, and is …
matrix (ECM). ECM protects wound tissue from infection and additional injury, and is …
[HTML][HTML] Matrix metalloproteinases shape the oligodendrocyte (niche) during development and upon demyelination
RP Gorter, W Baron - Neuroscience Letters, 2020 - Elsevier
The oligodendrocyte lineage cell is crucial to proper brain function. During central nervous
system development, oligodendrocyte progenitor cells (OPCs) migrate and proliferate to …
system development, oligodendrocyte progenitor cells (OPCs) migrate and proliferate to …
The role of biogenic amines in the modulation of monocytes in autoimmune neuroinflammation.
O Belousova, A Lopatina, U Kuzmina… - Multiple Sclerosis and …, 2023 - Elsevier
Multiple sclerosis (MS) is inflammatory demyelinating and neurodegenerative disease of the
central nervous system (CNS) with autoimmune mechanism of development. The study of …
central nervous system (CNS) with autoimmune mechanism of development. The study of …