Chordoma is a rare bone cancer that is aggressive, locally invasive, and has a poor
prognosis. Chordomas are thought to arise from transformed remnants of notochord and …

Charged particle beams are ideal for treating skull base and cervical spine tumors: dose can
be focused in the target, while achieving significant sparing of the brain, brain stem, cervical …

Chordomas are very rare bone malignant tumours that have had a shortage of effective
treatments for a long time. New treatments are now available for both the local and the …

BACKGROUND The prognosis of patients with chordoma of the sacrum and mobile spine
has been reported to be dismal and attributable in the majority of cases to intralesional …

Object. Local tumor control, patient survival, and treatment failure outcomes were analyzed
to assess treatment efficacy in 58 patients in whom fractionated proton radiation therapy …

Chordomas are rare, slowly growing, locally aggressive neoplasms of bone that arise from
embryonic remnants of the notochord. These tumors typically occur in the axial skeleton and …

Study Design. A consecutive series of 52 chordomas of the mobile spine observed over a 50-
year period includes a retrospective review of 15 cases treated prior to 1991 and a …

Background: Sacrococcygeal chordoma presents a difficult diagnostic and therapeutic
problem, with a high rate of local recurrence. The purpose of this report is to define the …

OBJECTIVE: Sacral chordomas are relatively rare, locally invasive, malignant neoplasms.
Despite surgical resection, adjuvant radiation therapy, and chemotherapy, recurrence is …

Purpose To explore the antitumor activity of imatinib in patients with advanced platelet-
derived growth factor β (PDGFB)/PDGF receptor β (PDGFRB)–positive chordomas. Patients …