Abstract gamma-Aminobutyric acid (GABA)-mediated inhibitory neurotransmission and the
gene products involved were discovered during the mid-twentieth century. Historically …

Alcohol is a potent somnogen and one of the most commonly used “over the counter” sleep
aids. In healthy non-alcoholics, acute alcohol decreases sleep latency, consolidates and …

Alcohol acts on numerous cellular and molecular targets to regulate neuronal
communication within the brain. Chronic alcohol exposure and acute withdrawal generate …

Background: Movement disorders are chronic diseases with an increasing prevalence in old
age. Because these disorders pose a major challenge to patients, families, and health care …

GABAergic inhibitory transmission is involved in the acute and chronic effects of ethanol on
the brain and behavior. One-dose ethanol exposure induces transient plastic changes in …

Ethanol (EtOH) has effects on numerous cellular molecular targets, and alterations in
synaptic function are prominent among these effects. Acute exposure to EtOH activates or …

Alcohol dependence is a chronically relapsing disorder characterized by compulsive drug-
seeking and drug-taking, loss of control in limiting intake, and the emergence of a …

Alcohol dependence is a chronically relapsing disorder characterized by compulsive drug
seeking and drug taking, loss of control in limiting intake, and the emergence of a withdrawal …

In recent years there has been an increase in the understanding of ethanol actions on the
type A γ-aminobutyric acid chloride channel (GABAAR), a member of the pentameric ligand …

Alcohol use disorders are characterized by compulsive drug-seeking and drug-taking, loss
of control in limiting intake, and withdrawal syndrome in the absence of drug. The central …