Astrocytes contribute to the complex cellular pathology of Alzheimer's disease (AD).
Neurons and astrocytes function in close collaboration through neurotransmitter recycling …

Glutamate is the primary excitatory neurotransmitter of the brain. Cellular homeostasis of
glutamate is of paramount importance for normal brain function and relies on an intricate …

The biological processes that are disrupted in the Alzheimer's disease (AD) brain remain
incompletely understood. In this study, we analyzed the proteomes of more than 1,000 brain …

Several common psychiatric and neurodegenerative diseases share epidemiologic risk;
however, whether they share pathophysiology is unclear and is the focus of our …

The myelination of axons has evolved to enable fast and efficient transduction of electrical
signals in the vertebrate nervous system. Acting as an electric insulator, the myelin sheath is …

The idea of central nervous system as one-man band favoring neurons is long gone. Now
we all are aware that neurons and neuroglia are team players and constant communication …

Microglia are resident immune cells in the central nervous system (CNS) that are capable of
carrying out prominent and various functions during development and adulthood under both …

The mammalian brain is complex, with multiple cell types performing a variety of diverse
functions, but exactly how each cell type is affected in aging remains largely unknown. Here …

The vascular interface of the brain, known as the blood–brain barrier (BBB), is understood to
maintain brain function in part via its low transcellular permeability,–. Yet, recent studies …

Oligodendrocytes generate multiple layers of myelin membrane around axons of the central
nervous system to enable fast and efficient nerve conduction. Until recently, saltatory nerve …