In the present scenario, resistance to antibiotics is one of the crucial issues related to public
health. Earlier, such resistance to antibiotics was limited to nosocomial infections, but it has …

The discovery of antibiotics has created a turning point in medical interventions to
pathogenic infections, but unfortunately, each discovery was consistently followed by the …

Background Assessments of age-specific mortality and life expectancy have been done by
the UN Population Division, Department of Economics and Social Affairs (UNPOP), the …

Background Lower respiratory infections are a leading cause of morbidity and mortality
around the world. The Global Burden of Diseases, Injuries, and Risk Factors (GBD) Study …

Summary Background The Global Burden of Diseases, Injuries, and Risk Factors (GBD)
Study 2015 provides an up-to-date analysis of the burden of lower respiratory tract infections …

Streptococcus pneumoniae is an infectious pathogen responsible for millions of deaths
worldwide. Diseases caused by this bacterium are classified as pneumococcal diseases …

Background Routine immunisation with pneumococcal conjugate vaccines (PCV7/10/13)
has reduced invasive pneumococcal disease (IPD) due to vaccine serotypes significantly …

Streptococcus pneumoniae (S. pneumoniae, pneumococcus) is a Gram-positive bacterium,
which can cause a variety of diseases including otitis media, nasosinusitis, pneumonia …

Introduction Antibiotic resistance is one of the biggest public health threats worldwide.
Currently, antibiotic-resistant bacteria kill 700,000 people every year. These data represent …

Genome‐wide screens have discovered a large set of essential genes in the opportunistic
human pathogen Streptococcus pneumoniae. However, the functions of many essential …