A review of classification, biosynthesis, biological activities and potential applications of flavonoids

S Chen, X Wang, Y Cheng, H Gao, X Chen - Molecules, 2023‏ - mdpi.com
Flavonoids represent the main class of plant secondary metabolites and occur in the tissues
and organs of various plant species. In plants, flavonoids are involved in many biological …

Anticancer potential of alkaloids: a key emphasis to colchicine, vinblastine, vincristine, vindesine, vinorelbine and vincamine

P Dhyani, C Quispe, E Sharma, A Bahukhandi… - Cancer cell …, 2022‏ - Springer
Cancer, one of the leading illnesses, accounts for about 10 million deaths worldwide. The
treatment of cancer includes surgery, chemotherapy, radiation therapy, and drug therapy …

[HTML][HTML] A review on metal complexes and its anti-cancer activities: Recent updates from in vivo studies

S Adhikari, P Nath, A Das, A Datta, N Baildya… - Biomedicine & …, 2024‏ - Elsevier
Research into cancer therapeutics has uncovered various potential medications based on
metal-containing scaffolds after the discovery and clinical applications of cisplatin as an anti …

Genistein: an integrative overview of its mode of action, pharmacological properties, and health benefits

J Sharifi-Rad, C Quispe, M Imran, A Rauf… - Oxidative medicine …, 2021‏ - Wiley Online Library
Genistein is an isoflavone first isolated from the brooming plant Dyer's Genista tinctoria L.
and is widely distributed in the Fabaceae family. As an isoflavone, mammalian genistein …

Chalcone derivatives: Role in anticancer therapy

Y Ouyang, J Li, X Chen, X Fu, S Sun, Q Wu - Biomolecules, 2021‏ - mdpi.com
Chalcones (1, 3-diaryl-2-propen-1-ones) are precursors for flavonoids and isoflavonoids,
which are common simple chemical scaffolds found in many naturally occurring compounds …

Natural coumarins: exploring the pharmacological complexity and underlying molecular mechanisms

J Sharifi-Rad, N Cruz-Martins… - Oxidative Medicine …, 2021‏ - Wiley Online Library
Coumarins belong to the benzopyrone family commonly found in many medicinal plants.
Natural coumarins demonstrated a wide spectrum of pharmacological activities, including …

Therapeutic applications of curcumin in diabetes: a review and perspective

C Quispe, J Herrera-Bravo, Z Javed… - BioMed Research …, 2022‏ - Wiley Online Library
Diabetes is a metabolic disease with multifactorial causes which requires lifelong drug
therapy as well as lifestyle changes. There is now growing scientific evidence to support the …

[HTML][HTML] Pharmacotherapeutics applications and chemistry of chalcone derivatives

JS Dhaliwal, S Moshawih, KW Goh, MJ Loy… - Molecules, 2022‏ - mdpi.com
Chalcones have been well examined in the extant literature and demonstrated antibacterial,
antifungal, anti-inflammatory, and anticancer properties. A detailed evaluation of the …

Neuropharmacological effects of quercetin: a literature-based review

MS Islam, C Quispe, R Hossain, MT Islam… - Frontiers in …, 2021‏ - frontiersin.org
Quercetin (QUR) is a natural bioactive flavonoid that has been lately very studied for its
beneficial properties in many pathologies. Its neuroprotective effects have been …

Cryopreservation of bioflavonoid-rich plant sources and bioflavonoid-microcapsules: emerging technologies for preserving bioactivity and enhancing nutraceutical …

J **ang, R Mlambo, I Shaw, Y Seid, H Shah, Y He… - Frontiers in …, 2023‏ - frontiersin.org
Bioflavonoids are natural polyphenolic secondary metabolites that are medicinal. These
compounds possess antitumor, cardioprotective, anti-inflammatory, antimicrobial, antiviral …