Depression in patients with Parkinson's disease: current understanding of its neurobiology and implications for treatment

S Prange, H Klinger, C Laurencin, T Danaila… - Drugs & aging, 2022 - Springer
Depression is one of the most frequent and burdensome non-motor symptoms in
Parkinson's disease (PD), across all stages. Even when its severity is mild, PD depression …

Structural and functional imaging correlates of visual hallucinations in Parkinson's disease

R Bhome, GEC Thomas, A Zarkali, RS Weil - Current Neurology and …, 2023 - Springer
Abstract Purpose of Review To review recent structural and functional MRI studies of visual
hallucinations in Parkinson's disease. Recent Findings Previously, neuroimaging had …

[HTML][HTML] Brain metabolic correlates of persistent olfactory dysfunction after SARS-Cov2 infection

MI Donegani, A Miceli, M Pardini, M Bauckneht… - Biomedicines, 2021 - mdpi.com
We aimed to evaluate the brain hypometabolic signature of persistent isolated olfactory
dysfunction after SARS-CoV-2 infection. Twenty-two patients underwent whole-body [18F] …

Implicating causal brain imaging endophenotypes in Alzheimer's disease using multivariable IWAS and GWAS summary data

KA Knutson, Y Deng, W Pan - NeuroImage, 2020 - Elsevier
Recent evidence suggests the existence of many undiscovered heritable brain phenotypes
involved in Alzheimer's Disease (AD) pathogenesis. This finding necessitates methods for …

[HTML][HTML] Alteration of brain structural connectivity in progression of Parkinson's disease: a connectome-wide network analysis

Y Yang, C Ye, J Sun, L Liang, H Lv, L Gao, J Fang… - NeuroImage: Clinical, 2021 - Elsevier
Pinpointing the brain dysconnectivity in idiopathic rapid eye movement sleep behaviour
disorder (iRBD) can facilitate preventing the conversion of Parkinson's disease (PD) from …

Cerebellar microstructural abnormalities in Parkinson's disease: a systematic review of diffusion tensor imaging studies

M Haghshomar, P Shobeiri, SA Seyedi… - The Cerebellum, 2022 - Springer
Diffusion tensor imaging (DTI) is now having a strong momentum in research to evaluate the
neural fibers of the CNS. This technique can study white matter (WM) microstructure in …

Identifying depression in Parkinson's disease by using combined diffusion tensor imaging and support vector machine

Y Yang, Y Yang, A Pan, Z Xu, L Wang, Y Zhang… - Frontiers in …, 2022 - frontiersin.org
Objective To investigate white matter microstructural alterations in Parkinson's disease (PD)
patients with depression using the whole-brain diffusion tensor imaging (DTI) method and to …

[HTML][HTML] Relationship between white matter alterations and pathophysiological symptoms in patients with ultra-high risk of psychosis, first-episode, and chronic …

K Waszczuk, E Tyburski, K Rek-Owodziń, P Plichta… - Brain sciences, 2022 - mdpi.com
Some symptoms of schizophrenia might be present before full-blown psychosis, so white
matter changes must be studied both in individuals with emerging psychosis and chronic …

The interplay between structural and functional connectivity in early stage Parkinson's disease patients

A Droby, S Nosatzki, Y Edry, A Thaler, N Giladi… - Journal of the …, 2022 - Elsevier
The mechanisms underlying cognitive disturbances in Parkinson's disease (PD) are poorly
understood but likely to depend on the ongoing degenerative processes affecting structural …

Simulating the progression of brain structural alterations in Parkinson's disease

C Park, NY Shin, SW Yoo, H Seo, U Yoon… - npj Parkinson's …, 2022 - nature.com
Considering brain structural alterations as neurodegenerative consequences of Parkinson's
disease (PD), we sought to infer the progression of PD via the ordering of brain structural …