SIRT1 (NAD-dependent protein deacetylase sirtuin-1), a class III histone deacetylase acting
as a tumor suppressor gene, is downregulated in oral cancer cells. Non-apoptotic doses of …

Aberrations emerging in mitochondrial homeostasis are restrained by mitophagy to control
mitochondrial integrity, bioenergetics signaling, metabolism, oxidative stress, and apoptosis …

Autophagy captures damaged or dysfunctional proteins and organelles through the
lysosomal pathway to achieve proper cellular homeostasis. Autophagy possesses distinct …

Sodium sulfite is a widely used preservative in the food industry. Ferroptosis has been a
newly discovered form of iron-dependent oxidative cell death in recent years. However, the …

Mitochondrial fission is a tightly regulated process involving multiple proteins and cell
signaling. Despite extensive studies on mitochondrial fission factors, our understanding of …

Previously, lysosomes were primarily referred to as the digestive organelles and recycling
centers within cells. Recent discoveries have expanded the lysosomal functional scope and …

Background Mitochondrial dysfunction associated with mitochondrial DNA mutations,
enzyme defects, generation of ROS, and altered oxidative homeostasis is known to induce …

Recent studies suggest that apoptosis in macrophages plays a significant role in host
defence against intracellular pathogens like viruses, fungi, protozoan, and bacteria …

Four new drimane-type sesquiterpenoids and two new nucleoside derivatives (1–6), were
isolated from the fungus Helicoma septoconstrictum. Their structures were determined …

Abstract Vaccinia-related kinase 1 (VRK1) is a gene which has been implicated in the
pathological process of a broad range of neurodevelopmental disorders as well as …